| Title: |
The Drosophila insulin degrading enzyme restricts growth by modulating the PI3K pathway in a cell autonomous manner. ; Molecular Biology of the Cell |
| Authors: |
Galagovsky, D.; Katz, M.J.; Acevedo, J.M.; Sorianello, E.; Glavic, A.; Wappner, P. |
| Publication Year: |
2020 |
| Subject Terms: |
Ciencias Naturales; Ciencias Biológicas; Biología General |
| Description: |
Mammalian insulin-degrading enzyme (IDE) cleaves insulin, among other peptidic substrates, but its function in insulin signaling is elusive. We use the Drosophila system to define the function of IDE in the regulation of growth and metabolism. We find tha ; FONDAP ; insulin, drosophila, degrading, enzyme, growth, function, restricts ; WOS ; FONDAP |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
https://doi.org/10.1091/mbc.E13-04-0213; WOS:000339629700023; https://hdl.handle.net/10533/238533 |
| Availability: |
https://hdl.handle.net/10533/238533 |
| Rights: |
Atribución-NoComercial-SinDerivadas 3.0 Chile ; http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ ; info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.96A4D916 |
| Database: |
BASE |