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Liakhotska A. V., Netiazhenko V. Z., Melnyk V. S., Plenova O. N. INFLUENCE OF ANTIPLATELET THERAPY RESISTANCE ON PROGNOSIS OF THROMBOTIC COMPLICATIONS IN PATIENTS WITH CORONARY HEART DISEASE. ВІСНИК МОРСЬКОЇ МЕДИЦИНИ. 2018;1(78):21-29. ISSN 0049-6804. DOI http://dx.doi.org/10.5281/zenodo.1230274 http://www.herald.com.ua УДК 612.12-008:616-08-039.71:616-005.6 DOI http://dx.doi.org/10.5281/zenodo.1230274 А. В. Ляхоцька, В. З. Нетяженко, В. С. Мельник, О. М. Плєнова ВПЛИВ РЕЗИСТЕНТНОСТІ ДО АНТИТРОМБОЦИТАРНОЇ ТЕРАПІЇ НА ПРОГНОЗ РОЗВИТКУ ТРОМБОТИЧНИХ УСКЛАДНЕНЬ У ХВОРИХ З ІШЕМІЧНОЮ ХВОРОБОЮ СЕРЦЯ Національний медичний університет імені О.О. Богомольця, м. Київ Summary. Liakhotska A. V., Netiazhenko V. Z., Melnyk V. S., Plenova O. N. INFLUENCE OF ANTIPLATELET THERAPY RESISTANCE ON PROGNOSIS OF THROMBOTIC COMPLICATIONS IN PATIENTS WITH CORONARY HEART DISEASE. - Bogomolets National Medical University. – e-mail: a.liakhotska@gmail.com. In recent years, the incidence of acute cardiovascular events associated with thrombosis in patients with coronary heart disease (CHD) has increased in Ukraine. According to the current international recommendations for prevention, the antithrombotic agents (prophylaxis of platelet aggregation and benign thrombotic formation): acetylsalicylicacid (ASA), thienopyridines (clopidogrel, ticagrelor, ticlopidine), etc., are widely used to influence the main pathogenesis of various forms of CHD. As a result of annual prospective monitoring, the role of antiplatelet resistance in the development of thrombotic complications in patients with st able and unstable forms of coronary heart disease and associated hypertension was determined, depending on genetic fact or sand thrombosis. The study included 167 patients with an average age of 67,09±9.08 years. Duration of observation is 1 year. The combine dend point included cases of non-fatal thrombotic complications: ischemic stroke, acute coronary syndrome and pulmonary embolism. Determination of antiplateletres istance was carried out with ... |