| Title: |
When should clinicians suspect group a streptococcus empyema in children? a multicentre case-control study in french tertiary care centres |
| Authors: |
Bellulo, Sophia; Sommet, Julie; Levy, Corinne; Gillet, Yves; Hees, Laure; Lorrot, Mathie; Gras-Le Guen, Christele; Craiu, Irina; Dubos, Francois; Minodier, Philippe; Biscardi, Sandra; Dommergues, Marie-Aliette; Bechet, Stéphane; Bidet, Philippe; Alberti, Corinne; Cohen, Robert; Faye, Albert |
| Contributors: |
CHU Lille; Université de Lille; Santé publique : épidémiologie et qualité des soins - EA 2694; METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694; Evaluation des technologies de santé et des pratiques médicales - ULR 2694 METRICS |
| Publication Year: |
2016 |
| Collection: |
LillOA (Lille Open Archive - Université de Lille) |
| Description: |
BACKGROUND: The incidence of invasive group A streptococcus (GAS) infections is increasing worldwide, whereas there has been a dramatic decrease in pneumococcal invasive diseases. Few data describing GAS pleural empyema in children are available. OBJECTIVE: To describe the clinical and microbiological features, management and outcome of GAS pleural empyema in children and compare them with those of pneumococcal empyema. METHODS: Fifty children admitted for GAS pleural empyema between January 2006 and May 2013 to 8 hospitals participating in a national pneumonia survey were included in a descriptive study and matched by age and centre with 50 children with pneumococcal empyema. RESULTS: The median age of the children with GAS pleural empyema was 2 (range 0.1-7.6) years. Eighteen children (36%) had at least one risk factor for invasive GAS infection (corticosteroid use and/or current varicella). On admission, 37 patients (74%) had signs of circulatory failure, and 31 (62%) had a rash. GAS was isolated from 49/50 pleural fluid samples and from one blood culture. The commonest GAS genotype was emm1 (n=17/22). Two children died (4%). Children with GAS empyema presented more frequently with a rash (p |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
Archives of disease in childhood; Arch. Dis. Child.; http://hdl.handle.net/20.500.12210/17013 |
| Availability: |
https://hdl.handle.net/20.500.12210/17013 |
| Rights: |
info:eu-repo/semantics/closedAccess |
| Accession Number: |
edsbas.97412232 |
| Database: |
BASE |