| Title: |
Associations of social engagement, and loneliness with the progression and reversal of frailty: longitudinal investigations of two prospective cohorts from the UK and the USA. |
| Authors: |
Cai, Z; Papacosta, AO; Lennon, LT; Whincup, PH; Wannamethee, SG; Simonsick, EM; Mathers, JC; Ramsay, SE |
| Publisher Information: |
Oxford University Press |
| Publication Year: |
2025 |
| Collection: |
St George's University of London: Repository |
| Description: |
BACKGROUND: Social connections may impact the dynamic trajectory of frailty. METHODS: Using data from the British Regional Heart Study (BRHS) in the UK (n = 715), and the US Health, Aging and Body Composition (Health ABC) Study (n = 1256), we conducted multinominal regression analyses to examine the association of baseline and change in social engagement and loneliness with progression to pre-frailty and frailty, as well as their association with reversal to pre-frailty and robust status among older adults. RESULTS: A higher level of social engagement at baseline (BRHS: relative risk ratio (RRR) 0.69 [95%CI 0.55-0.85]; Health ABC: 0.56 [0.45-0.70]), as well as increase in social engagement (BRHS: 0.73, [0.59-0.90]; Health ABC: 0.51 [0.41-0.63]), were associated with a lower risk of developing frailty. In BRHS, a higher level of loneliness at baseline (1.42 [1.10-1.83]) and an increase in loneliness (1.50 [1.18-1.90]), increased the risk of developing frailty. For reversal of frailty, higher social engagement at baseline (Health ABC: 1.63 [1.08-2.47]) and an increase in social engagement (BRHS:1.74[1.18-2.50]; Health ABC: 1.79[1.17-.274]) were beneficial. CONCLUSION: Social connections maybe potentially important and modifiable factors in both preventing and reversing progression of frailty in older adults. |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document |
| Language: |
English |
| ISSN: |
1476-6256 |
| Relation: |
https://openaccess.sgul.ac.uk/id/eprint/116748/9/kwae221.pdf; https://openaccess.sgul.ac.uk/id/eprint/116748/6/supplementary_tables_frailty_social_connections_aje_150524_kwae221.docx; https://openaccess.sgul.ac.uk/id/eprint/116748/1/kwae221.pdf; Cai, Z; Papacosta, AO; Lennon, LT; Whincup, PH; Wannamethee, SG; Simonsick, EM; Mathers, JC; Ramsay, SE (2025) Associations of social engagement, and loneliness with the progression and reversal of frailty: longitudinal investigations of two prospective cohorts from the UK and the USA. Am J Epidemiol, 194 (4). pp. 984-993. ISSN 1476-6256 https://doi.org/10.1093/aje/kwae221 SGUL Authors: Whincup, Peter Hynes |
| DOI: |
10.1093/aje/kwae221 |
| Availability: |
https://openaccess.sgul.ac.uk/id/eprint/116748/; https://openaccess.sgul.ac.uk/id/eprint/116748/9/kwae221.pdf; https://openaccess.sgul.ac.uk/id/eprint/116748/6/supplementary_tables_frailty_social_connections_aje_150524_kwae221.docx; https://openaccess.sgul.ac.uk/id/eprint/116748/1/kwae221.pdf; https://doi.org/10.1093/aje/kwae221 |
| Rights: |
cc_by_4 |
| Accession Number: |
edsbas.97B72D0C |
| Database: |
BASE |