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Corticosteroid therapy is associated with a decrease in mortality in a multicenter cohort of mechanically ventilated COVID-19 patients

Title: Corticosteroid therapy is associated with a decrease in mortality in a multicenter cohort of mechanically ventilated COVID-19 patients
Authors: LAMBERMONT, Bernard; ERNST, Marie; DEMARET, Pierre; FRAIPONT, Vincent; GURDEBEKE, Christine; SOTTIAUX, Thierry; QUINONEZ, Manuel; DUBOIS, Christophe; NJAMBOU, Thierry; AKANDO, Benoit; LEMINEUR, Thierry; WERTZ, Damien; FORET, Frédéric; ROUSSEAU, Anne-Françoise; LEDOUX, Didier; LAYIOS, Nathalie; ROBINET, Sébastien; MORIMONT, Philippe; Misset, Benoît
Source: Intensive Care Medicine Experimental, 8 (Suppl 2), 001357 (2020); LIVES digital 2020, Décembre 2020
Publisher Information: Springer
Publication Year: 2020
Collection: University of Liège: ORBi (Open Repository and Bibliography)
Subject Terms: Human health sciences; Anesthesia & intensive care; Sciences de la santé humaine; Anesthésie & soins intensifs
Description: peer reviewed ; Retrospectively analyzing the data of a multicenter cohort, we observed that mortality of patients with SARS-CoV-2 pneumoniatreated with mechanical ventilation was as high as 45% and median survival time was 82 days. In this series, the risk factors for mortality included age, renal and circulatory dysfunction, lymphopenia and the absence of corticosteroid use during the first week of mechanical ventilation. Corticosteroid therapy during the first week of mechanical ventilation was associated with a lower mortality (34% vs 48%) (p = 0,01).
Document Type: conference object; report
Language: English
ISSN: 2197-425X
Relation: urn:issn:2197-425X; https://orbi.uliege.be/handle/2268/257886; info:hdl:2268/257886; https://orbi.uliege.be/bitstream/2268/257886/1/B.%20Lambermont%20et%20al%20Intensive%20Car%20Med%20Exp%202020.pdf
Availability: https://orbi.uliege.be/handle/2268/257886; https://orbi.uliege.be/bitstream/2268/257886/1/B.%20Lambermont%20et%20al%20Intensive%20Car%20Med%20Exp%202020.pdf
Rights: open access ; http://purl.org/coar/access_right/c_abf2 ; info:eu-repo/semantics/openAccess
Accession Number: edsbas.97DBBEC0
Database: BASE