| Title: |
Bone quality assessed using quantitative ultrasound at the distal radius does not differ in antiretroviral therapy‐naïve HIV‐positive and HIV‐negative Rwandan women |
| Authors: |
Mutimura, E; Shi, Q; Hoover, DR; Anastos, K; Rudakemwa, E; Dusingize, JC; Sinabye, JD; Yin, MT |
| Source: |
HIV Medicine ; volume 17, issue 10, page 724-727 ; ISSN 1464-2662 1468-1293 |
| Publisher Information: |
Wiley |
| Publication Year: |
2016 |
| Collection: |
Wiley Online Library (Open Access Articles via Crossref) |
| Description: |
Objectives The incidence of fractures appears to be increased in HIV ‐infected individuals. Methods We assessed bone quality using quantitative ultrasound ( QUS ) in HIV ‐infected and uninfected Rwandan women. A Sunlight Omnisense 7000 QUS was used to measure the speed of ultrasound ( SOS ) at the distal radius in 646 antiretroviral therapy ( ART )‐naïve HIV ‐infected women and 211 HIV ‐uninfected women. The Z ‐scores for SOS were based on data for women of the same age from the manufacturer's reference material. Results The mean CD 4 cell count was 285 (± 166) cells/μL in the HIV ‐positive women. SOS Z ‐scores adjusted and unadjusted for body mass index did not differ between the groups. SOS did not differ by CD 4 count (< 200 vs. ≥ 200 cells/μL: 4016 (± 117) vs. 4028 (± 107) m/s, respectively; p=0.19. Conclusions In HIV ‐positive ART ‐naïve Rwandan women with advanced HIV disease, bone quality at the distal radius was similar to that in HIV ‐negative controls. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1111/hiv.12376 |
| Availability: |
http://dx.doi.org/10.1111/hiv.12376; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fhiv.12376; https://onlinelibrary.wiley.com/doi/pdf/10.1111/hiv.12376; https://onlinelibrary.wiley.com/doi/full-xml/10.1111/hiv.12376 |
| Rights: |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
| Accession Number: |
edsbas.9964886D |
| Database: |
BASE |