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LEMMI: a continuous benchmarking platform for metagenomics classifiers

Title: LEMMI: a continuous benchmarking platform for metagenomics classifiers
Authors: Seppey, Mathieu; Manni, Mose; Zdobnov, Evgeny
Source: ISSN: 1088-9051 ; Genome Research, (2020.
Publication Year: 2020
Collection: Université de Genève: Archive ouverte UNIGE
Subject Terms: info:eu-repo/classification/ddc/576.5
Description: Studies of microbiomes are booming, along with the diversity of computational approaches to make sense out of the sequencing data and the volumes of accumulated microbial genotypes. A swift evaluation of newly published methods and their improvements against established tools is necessary to reduce the time between the method's release and its adoption in microbiome analyses. The LEMMI platform offers a novel approach for benchmarking software dedicated to metagenome composition assessments based on read classification. It enables the integration of newly published methods in an independent and centralized benchmark designed to be continuously open to new submissions. This allows developers to be proactive regarding comparative evaluations and guarantees that any promising methods can be assessed side-by-side with established tools quickly after their release. Moreover, LEMMI enforces an effective distribution through software containers to ensure long term availability of all methods. Here, we detail the LEMMI workflow and discuss the performances of some previously unevaluated tools. We see this platform eventually as a community-driven effort where method developers can showcase novel approaches and get unbiased benchmarks for publications, while users can make informed choices and obtain standardized and easy-to-use tools.
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/32616517; info:eu-repo/semantics/dataset/url/https://zenodo.org/record/2651062#.XzJ1yUBuLVw; unige:139248
Availability: https://archive-ouverte.unige.ch/unige:139248
Rights: info:eu-repo/semantics/openAccess
Accession Number: edsbas.99BB899B
Database: BASE