| Title: |
Population Pharmacokinetics of Doxycycline in Children |
| Authors: |
Thompson, Elizabeth J.; Wu, Huali; Melloni, Chiara; Balevic, Stephen; Sullivan, Janice E.; Laughon, Matthew; Clark, Kira M.; Kalra, Rohit; Mendley, Susan; Payne, Elizabeth H.; Erinjeri, Jinson; Gelber, Casey E.; Harper, Barrie; Cohen-Wolkowiez, Michael; Hornik, Christoph P.; Benjamin, Daniel K.; Hornik, Christoph; Zimmerman, Kanecia; Kennel, Phyllis; Beci, Rose; Hornik, Chi Dang; Kearns, Gregory L.; Paul, Ian M.; Sullivan, Janice; Wade, Kelly; Delmore, Paula; Samson, Adam; Day, Tammy; Thomas, Melissa; Rich, Carla; Bratton, Tressa; Clark, Cynthia; Bernhardt, Janice; Uzri, Amira Al; Clark, Kira; Yogev, Rami; Muller, William; Fearn, Laura; Hill, Tamara; Cannonier, Donna; Blackford, Martha; Anthony, Heather; Neville, Kathleen |
| Contributors: |
HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development |
| Source: |
Antimicrobial Agents and Chemotherapy ; volume 63, issue 12 ; ISSN 0066-4804 1098-6596 |
| Publisher Information: |
American Society for Microbiology |
| Publication Year: |
2019 |
| Description: |
Doxycycline is a tetracycline-class antimicrobial labeled by the U.S. Food and Drug Administration for children >8 years of age for many common childhood infections. Doxycycline is not labeled for children ≤8 years of age, due to the association between tetracycline-class antibiotics and tooth staining, although doxycycline may be used off-label under severe conditions. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1128/aac.01508-19 |
| DOI: |
10.1128/AAC.01508-19 |
| Availability: |
https://doi.org/10.1128/aac.01508-19; https://journals.asm.org/doi/pdf/10.1128/AAC.01508-19 |
| Rights: |
https://journals.asm.org/non-commercial-tdm-license |
| Accession Number: |
edsbas.9A701C6D |
| Database: |
BASE |