| Title: |
Can PSMA-Targeting PET/CT Be a Valuable Instrument to Assess the Presence of Brain Metastases in Lung Cancer Patients? ; A Case Report |
| Authors: |
Dall'Armellina, Sara; Cauda, Simona; Duca, Sergio; Gasparro, Martina; Racca, Manuela |
| Source: |
Clinical Nuclear Medicine ; volume 48, issue 6, page e304-e306 ; ISSN 1536-0229 0363-9762 |
| Publisher Information: |
Ovid Technologies (Wolters Kluwer Health) |
| Publication Year: |
2023 |
| Description: |
A 78-year-old man with synchronous diagnosis of prostate cancer and lung adenocarcinoma was referred to our institute for prostate cancer staging with [ 18 F]F–prostate-specific membrane antigen (PSMA) 1007 PET/CT. In addition to the previously known lesion of the right lung, PSMA-targeted PET/CT highlighted 2 areas of abnormal uptake in the brain, in the left frontal and temporal lobes. A subsequent MRI confirmed the lesions observed on PET/CT. Because PSMA-targeting radiopharmaceuticals do not accumulate in healthy brain parenchyma, and recent literature reported promising performances of PSMA-targeted PET/CT in gliomas and metastases from tumors other than prostate cancer, this employment of PSMA radioligands needs to be further explored. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1097/rlu.0000000000004675 |
| DOI: |
10.1097/RLU.0000000000004675 |
| Availability: |
https://doi.org/10.1097/rlu.0000000000004675; https://journals.lww.com/10.1097/RLU.0000000000004675 |
| Accession Number: |
edsbas.9B050B2A |
| Database: |
BASE |