| Title: |
Versatility of inner membrane protein biogenesis in Escherichia coli |
| Authors: |
Fröderberg, Linda; Houben, Edith; Samuelson, James C.; Chen, Minyong; Park, Sei‐Kyoung; Phillips, Gregory J.; Dalbey, Ross; Luirink, Joen; De Gier, Jan‐Willem L. |
| Source: |
Molecular Microbiology ; volume 47, issue 4, page 1015-1027 ; ISSN 0950-382X 1365-2958 |
| Publisher Information: |
Wiley |
| Publication Year: |
2003 |
| Collection: |
Wiley Online Library (Open Access Articles via Crossref) |
| Description: |
Summary To further our understanding of inner membrane protein (IMP) biogenesis in Escherichia coli , we have accomplished the widest in vivo IMP assembly screen so far. The biogenesis of a set of model IMPs covering most IMP structures possible has been studied in a variety of signal recognition particle (SRP), Sec and YidC mutant strains. We show that the assembly of the complete set of model IMPs is assisted (i.e. requires the aid of proteinaceous factors), and that the requirements for assembly of the model IMPs into the inner membrane differ significantly from each other. This indicates that IMP assembly is much more versatile than previously thought. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1046/j.1365-2958.2003.03346.x |
| Availability: |
https://doi.org/10.1046/j.1365-2958.2003.03346.x; https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1365-2958.2003.03346.x |
| Rights: |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
| Accession Number: |
edsbas.9B92E450 |
| Database: |
BASE |