| Title: |
Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers |
| Authors: |
Cohen-Adad, J.; Alonso-Ortiz, E.; Abramovic, M.; Arneitz, C.; Atcheson, N.; Barlow, L.; Barry, R.; Barth, M.; Battiston, M.; Büchel, C.; Budde, M.; Callot, V.; Combes, A.; De Leener, B.; Descoteaux, M.; de Sousa, P.; Dostál, M.; Doyon, J.; Dvorak, A.; Eippert, F.; Epperson, K.; Freund, P.; Finsterbusch, J.; Foias, A.; Fratini, M.; Fukunaga, I.; Gandini Wheeler-Kingshott, C.; Germani, G.; Gilbert, G.; Giove, F.; Gros, C.; Grussu, F.; Hagiwara, A.; Henry, P.; Horák, T.; Hori, M.; Joers, J.; Kamiya, K.; Karbasforoushan, H.; Keřkovský, M.; Khatibi, A.; Kim, J.; Kinany, N.; Kitzler, H.; Kolind, S.; Kong, Y.; Kudlička, P.; Kuntke, P.; Kurniawan, N.; Kusmia, S.; Labounek, R.; Laganà, M.; Laule, C.; Law, C.; Lenglet, C.; Leutritz, T.; Liu, Y.; Llufriu, S.; Mackey, S.; Martinez-Heras, E.; Mattera, L.; Nestrasil, I.; O’Grady, K.; Papinutto, N.; Papp, D.; Pareto, D.; Parrish, T.; Pichiecchio, A.; Prados, F.; Rovira, À.; Ruitenberg, M.; Samson, R.; Savini, G.; Seif, M.; Seifert, A.; Smith, A.; Smith, S.; Smith, Z.; Solana, E.; Suzuki, Y.; Tackley, G.; Tinnermann, A.; Valošek, J.; Van De Ville, D.; Yiannakas, M.; Weber II, K.; Weiskopf, N.; Wise, R.; Wyss, P.; Xu, J. |
| Source: |
Scientific Data |
| Publication Year: |
2021 |
| Collection: |
Max Planck Society: MPG.PuRe |
| Description: |
In a companion paper by Cohen-Adad et al. we introduce the spine generic quantitative MRI protocol that provides valuable metrics for assessing spinal cord macrostructural and microstructural integrity. This protocol was used to acquire a single subject dataset across 19 centers and a multi-subject dataset across 42 centers (for a total of 260 participants), spanning the three main MRI manufacturers: GE, Philips and Siemens. Both datasets are publicly available via git-annex. Data were analysed using the Spinal Cord Toolbox to produce normative values as well as inter/intra-site and inter/intra-manufacturer statistics. Reproducibility for the spine generic protocol was high across sites and manufacturers, with an average inter-site coefficient of variation of less than 5% for all the metrics. Full documentation and results can be found at https://spine-generic.rtfd.io/. The datasets and analysis pipeline will help pave the way towards accessible and reproducible quantitative MRI in the spinal cord. |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/34400655 |
| Availability: |
http://hdl.handle.net/21.11116/0000-0009-17F7-7; http://hdl.handle.net/21.11116/0000-000A-E74E-B |
| Rights: |
info:eu-repo/semantics/openAccess ; https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.9BC9A2B5 |
| Database: |
BASE |