| Title: |
Topical treatment use and under-use in childhood eczema:secondary analysis of RCTs and cohort data in the UK and the Netherlands |
| Authors: |
van Halewijn, Karlijn; Bohnen, Arthur; MacNeill, Stephanie J; Ridd, Matthew J; Stuart, Beth; Santer, Miriam; Bindels, Patrick; Elshout, Gijs |
| Source: |
van Halewijn, K, Bohnen, A, MacNeill, S J, Ridd, M J, Stuart, B, Santer, M, Bindels, P & Elshout, G 2026, 'Topical treatment use and under-use in childhood eczema : secondary analysis of RCTs and cohort data in the UK and the Netherlands', British Journal of General Practice Open. https://doi.org/10.3399/BJGPO.2026.0005 |
| Publication Year: |
2026 |
| Collection: |
University of Bristol: Bristol Reserach |
| Description: |
Background: Underuse of emollients and topical corticosteroids (TCS) contributes to uncontrolled atopic eczema, but variations between countries remain unclear. Aim: To compare the actual use of emollient and TCS use in childhood eczema in the UK and The Netherlands (NL) and examine treatment adherence in relation to guidelines. Design & setting: A secondary analysis of data from the Rotterdam Eczema cohort study (n=367) (NL), the BATHE trial (n=482) (UK) and BEE trial (n=520) (UK).Methods: Frequency of emollient and TCS use were compared at baseline and after 12-16 weeks of follow-up by age, sex and disease severity. Treatment adherence was defined as: 1 a) not using an emollient at all, 1b) not using an emollient when a TCS was used, 2) not using a TCS when eczema is mild or worse. Overall undertreatment was defined as category 1 and 2 combined. Results: In total, questionnaire data from 1312 children (aged 3 months-17 years) with mostly mild (26-37%) or moderate (45-48%) eczema were analysed. Not using an emollient was significantly more prevalent in NL at baseline (14%) and follow-up (19%) than in the UK (4% and 7.6%, respectively). Not using a TCS when eczema is mild or worse differed significantly (P |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/41760286; info:eu-repo/semantics/altIdentifier/hdl/https://hdl.handle.net/1983/d631cf02-6f13-4ccc-b142-0843b925c6a0 |
| DOI: |
10.3399/BJGPO.2026.0005 |
| Availability: |
https://hdl.handle.net/1983/d631cf02-6f13-4ccc-b142-0843b925c6a0; https://research-information.bris.ac.uk/en/publications/d631cf02-6f13-4ccc-b142-0843b925c6a0; https://doi.org/10.3399/BJGPO.2026.0005 |
| Rights: |
info:eu-repo/semantics/openAccess ; http://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.9BEFA370 |
| Database: |
BASE |