| Title: |
Analysis of Short-Term Outcomes in Pancreatic Surgery with Vascular Resection from a Prospective Multicenter Global Study |
| Authors: |
Tinguely, Pascale; Hidalgo Salinas, Camila; Staubli, Sebastian M.; Raptis, Dimitri A.; Fusai, Giuseppe K.; null, null; Hilal, Mohamed Abu; Bassi, Claudio; Besselink, Marc; Conlon, Kevin; Davidson, Brian; Del Chiaro, Marco; Dervenis, Christos; Falconi, Massimo; Hackert, Thilo; Harrison, Ewen; Shrikhande, Shailesh V.; Siriwardena, Ajith; Smith, Martin; Wolfgang, Christopher; Borakati, Aditya; Balci, Deniz; Machairas, Nikolaos; Marchegiani, Giovanni; Oba, Atsushi; Oberkofler, Christian; Passas, Ioannis; Ravikumar, Reena; Velázquez, Patricia Sánchez; de Santibañes, Martin; Schnitzbauer, Andreas Anton; Soggiu, Fiammetta; Tamburrino, Domenico; Wei, Alice; Zachiotis, Marinos; Bentabak, Kamel; Kacimi, Salah Eddine; Nikfarjam, Mehrdad; Shcherba, Aliaksei; Sergeant, Gregory; Coelho, Gustavo; Torres, Orlando; Belev, Nikolay; Fabrice, Burundi; Tang, Ephraim; Martin, Janet; Diaz, Christian; Devaud, Nicolas; Wei, Kongyuan; Hendi, Maher; Mikulic, Danko; Gouvas, Nikolaos; Nikov, Andrej; Fathallah, Dalia; Saad, Mahmoud; Tammik, Olav; Huhta, Heikki; Sulpice, Laurent; Lupinacci, Renato; Stavrou, Gregor; Felekouras, Evangelos; Papaziogas, Vasileios; Misra, Sanjeev; Prabowo, Erik; Hashim, Hashim Talib; Al-Sader, Maytham Al-Juaifari; Satoi, Sohei; Obeidat, Khaled; Mohsen, Maram; Han, Ho-Seong; Khalife, Mohamad; Elhadi, Muhammed; Dulskas, Audrius; Bong, Jin; Ghani, Shahi; Padilla, Alejandro Eduardo; Melchor-Ruan, Javier; Erdene, Sarnai; Benkabbou, Amine; Nashidengo, Pueya; Koea, Jonathan; Adeyeye, Ademola; Alatise, Olusegun; Ullah, Sami; Jayyab, Mustafa Abu; Amro, Sarah; Alnammourah, Walaa Mohammed; The, Catherine; Pędziwiatr, Michał; Polkowski, Wojciech; Barbu, Sorin; Karamarkovic, Aleksandar; Galun, Daniel; Goh, Brian; Trotovšek, Blaž; Omoshoro-Jones, Jones; Ielpo, Benedetto; Abdelmageed, Abdelfatah; Sandström, Per; Cristaudi, Alessandra; Gloor, Beat; Kuemmerli, Christoph; Tishreen, Alaa Hamdan; Chaaban, Mohammad Karam; Wu, Chien Hui; Jen, Po-Chih Yang Fu; Houssem, Ammar; Baraket, Oussama; Çoker, Ahmet; Taylor, Mark; Jamieson, Nigel; Iype, Satheesh; Giorgakis, Emmanouil; Qadan, Motaz; Ganai, Sabha; Al-Naggar, Hamza; Chihaka, Onesai; Behi, Amor El; Tidjane, Anisse; Ouahab, Ilhem; Bouaoud, Souad; Rais, Mounira; Abdoun, Meriem; Ouyahia, Amel; Mc Cormack, Lucas; de Santibanes, Martin; Schelotto, Pablo Barros; Joglekar, Shantanu; Gananadha, Sivakumar; Hall, Kat; Hodgson, Russell; Rowcroft, Alistair; Chong, Lynn; Shah, Kalpesh; Chen, Stanley; Burnett, David; Ng, Zi Qin; Apostolou, Christos; Kornprat, Peter; Stoyanova, Radoslava; Van den Bossche, Bert; Hartman, Vera; Gryspeerdt, Filip; Berrevoet, Frederik; Strypstein, Sébastien; Pinto, Rinaldo; Militz, Matheus; Rodrigues, Pablo; Marques, Narimã; Sampaio, Adriano; Krastev, Panche; Slavchev, Mihail; Takorov, Ivelin; Vladov, Nikola; Mihaylov, Vassil; Nikolaev, Evgeni; Kostov, Daniel; Serrano, Pablo; Diaz, Cristian; Brañes, Alejandro; Cai, Lei; Chen, Yiming; Štironja, Ivan; Bubalo, Tomislav; Loveček, Martin; Zaruba, Pavel; Attalla, Almoatazbellah; Tayiawi, Mosaab; Alboridy, Muneera; Mourad, Mohamed; Elkeleny, Mostafa; Tanas, Yousef; Ealreibi, Hajer; Moneam, Mohamed Abd El; Hamouda, Mohammed; Nafea, Ahmed; Abdelalemm, Mohamed; Mansour, Ahmed; Farag, Marina; Salah, Mohamed; Abdelkarem, Mohamed; Sayed, Hatem; Diab, Sherein; Gobran, Mira; Fahim, Abdelrahman; Awad, Ahmed K.; Abdelmawgoud, Sherif; Alazab, Emad; Nagy, Mostafa; Metwally, Islam; Shehta, Ahmed; Monier, Ahmed; Awad, Selmy; Omar, Mohammed; Alsabbagh, Feras; Kauppila, Joonas; Nortunen, Minna; Brustia, Raffaele; Truant, Stéphanie; Piessen, Guillaume; Dupré, Aurélien; Souche, Francois-Regis; Savala, Natalia; Gaujoux, Sébastien; Goasguen, Nicolas; Anyla, Morgan; Schwarz, Lilian; Giannone, Fabio; Demetrashvili, Zaza; Bartella, Isabel; Pozios, Ioannis; Belyaev, Orlin; Bulian, Dirk; Praetorius, Christian; Korn, Sandra; Brunner, Maximilian; Mazzella, Elena; Reichert, Martin; Gaedcke, Jochen; Ronellenfitsch, Ulrich; Reese, Tim; Wagner, Kim; Scognamiglio, Pasquale; Uzunoglu, Faik; Izbicki, Jakob; Struecker, Benjamin; Kardassis, Dimitrios; Nadalin, Silvio; Makridis, Georgios; Tsoukalas, Nikolaos; Kechagias, Aristotelis; Ioannidis, Argyrios; Arkadopoulos, Nikolaos; Papakonstantinou, Dimitrios; Michalopoulos, Nikolaos; Kokoropoulos, Panagiotis; Vassiliu, Pantelis; Stergiou, Dimitrios; Sotiropoulou, Maria; Tomara, Nefeli; Dorovinis, Panagiotis; Tzimas, George; Schizas, Dimitrios; Papalampros, Alexandros; Polydorou, Andreas; Fragulidis, Georgios; Toutouzas, Konstantinos; Vezakis, Antonios; Bramis, Konstantinos; Korkolis, Dimitrios; Fradelos, Evangelos; Glantzounis, Georgios; Magouliotis, Dimitrios; Christodoulidis, Grigorios; Mulita, Francesk; Kontis, Elissaios; Giakoustidis, Dimitris; Katsourakis, Anastasios; Νtinas, Achilleas; Petras, Panagiotis; Bursics, Attila; Vereczkei, Andras; Karuparthi, Sreenivasan; Purushothaman, Govind; Gupta, Rahul; Yadav, Kaushal; Jain, Sundeep; Vishnoi, Jeewan Ram; Varshney, Vaibhav; Das, Kshaunish; Chattopadhyay, Somnath; Velagala, Jayapala Reddy; Bansal, Varun; S, Induchoodan; Kumar, Tarun; Al-Juaifari, Maytham; Sadot, Eran; Vivarelli, Marco; Andriola, Valeria; Ciola, Michele; Papa, Mario Virgilio; Antonucci, Adelmo; Sasia, Diego; Testa, Valentina; Bencini, Lapo; Nelli, Tommaso; D'Acapito, Fabrizio; Pacilio, Carlo Alberto; Carganico, Giacomo; De Rosa, Raffaele; D'Ugo, Stefano; Saladino, Edoardo; Recordare, Alfonso; Mazzola, Michele; Mazzaferro, Vincenzo; Zerbi, Alessandro; Baldi, Caterina; Stella, Marco; Di Benedetto, Fabrizio; Uggeri, Fabio; Iacomino, Alessandro; Rompianesi, Gianluca; Belli, Andrea; Moletta, Lucia; Tolin, Francesca; Giuffrida, Mario; Cobianchi, Lorenzo; Regi, Paolo; Morelli, Luca; Kauffmann, Emanuele Federico; Pinotti, Enrico; Giuliante, Felice; Coppola, Alessandro; Manzia, Tommaso Maria; Porcu, Alberto; Feo, Claudio; Perra, Teresa; Ciarleglio, Francesco; Novello, Simone; Ferrero, Alessandro; Intini, Sergio; Querini, Giorgio; Ruzzenente, Andrea; Campagnaro, Tommaso; Conci, Simone; Napetti, Sara; Frontali, Alice; Hashimoto, Daisuke; Matsumoto, Ippei; Maehira, Hiromitsu; Tanabe, Minoru; Alissawi, Subhi; Obed, Aiman; Rababa, Hebah; Al-Shami, Khayry; Alsabah, Mohamed; Shumrakh, Saeed; Al-Samawi, Abdulaziz; Khamees, Almu'Atasim; Fakhradiyev, Ildar; Atstupens, Kristaps; Faraj, Walid; Alowjali, Fatoom; Alshatshat, Abdulhadi; Benamwor, Aihab; Younes, Eman; Burgan, Dania; Morgom, Marwa; Binnawara, Muhannud; Alshareea, Entisar; Ahmeed Ahmeed, Sultan; Othman, Eman; Gerwash, Ahmed; Salem, Osama; Khalil, Wegdan; Abdulwahed, Eman; Alharari, Mohamed; Vanagas, Tomas; Eismontas, Vitalijus; Jurgaitis, Jonas; Slepavicius, Algirdas; Mikutaitis, Vytenis; Kvietkauskas, Mindaugas; Rosso, Edoardo; Zakaria, Andee Dzulkarnaen; Chik, Ian; Zorrilla, Carlos Florez; Korch, Moniba; Gouazar, Iltimass; Serji, Badr; Zentar, Aziz; Elhassouni, Reda; Echiguer, Sabrillah; Majbar, Mohammed Anass; Nashidengo, Abdulrashid Pueya; Lakhey, Paleswan Joshi; Windsor, John; Chu, Michael Jen Jie; Johnston, Peter; Bindra, Vanshay; Cross, Andrea; Gunawardene, Ashok; Welsh, Fraser; Abbasy, Jibran; Siddiqui, Tayyab; Asghar, Mohammad; Zreqat, Qusai; Titi, Rawand; Manasrah, Fatima; Hammoudeh, Ahlam; Coayla, Guillermo; Teh, Catherine; Alfonso, Cenon; Flisińska, Marta; Rymarowicz, Justyna; Sierzega, Marek; Ciesielski, Wojciech; Grząsiak, Oliwia; Szewczyk, Patrycja; Szwedziak, Krzysztof; Korcz, Wojciech; Kornasiewicz, Oskar; Vigia, Emanuel; Radulescu, Raluca Bievel; Dumitrascu, Traian; Mardare, Mara; Ginghina, Octav; Brezean, Iulian; Petrea, Sorin; Bartos, Adrian; Bodea, Raluca; Matei, Sergiu; Musina, Ana-Maria; Velenciuc, Natalia; Belyaev, Alexander; Mizgirev, Denis; Litvin, Andrey; Semenenko, Ivan; Bedzhanyan, Arkady; Bagmet, Nikolay; Kaldarov, Ayrat; Kuchin, Denis; Drozdov, Evgeniy; Gachabayov, Mahir; Alharthi, Mohammed; Bogdanovic, Aleksandar; Kmezic, Stefan; Arbutina, Dragana; Bezmarevic, Mihailo; Juloski, Jovan; Protic, Mladjan; Loots, Emil; Marcello, Manuel; Ramia, Jose; Del Mar Rico-Morales, Maria; Ausania, Fabio; Arnau, Ana Belen Martin; Santos, Esther Pilar; Ruiz, Patricia; Falgueras, Laia; Al Shwely, Farah; Busquets, Juli; Justo, Iago; Dziakova, Jana; Di Martino, Marcello; Suárez-Muñoz, Miguel Ángel; García, Lorena Solar; Segura-Sampedro, Juan Jose; Rotellar, Fernando; Muñoz-Bellvis, Luis; Vera, Valle; Domingo, María García; Pozo, Carlos Domingo-Del; Ibáñez, Cristina Ballester; Dorcaratto, Dimitri; Rodriguez-Lopez, Mario; Serrablo, Alejandro; Hamid, Hytham; Lundgren, Linda; Tingstedt, Bobby; Williamsson, Caroline; Andersson, Bodil; Sparrelid, Ernesto; Moeckli, Beat; Abbassi, Fariba; Schmidt, Jan; Gutknecht, Stefan; Jonas, Jan Philipp; Alhashemi, Mais; Douba, Zain; Kayali, Ahmad; Azizeh, Oula; Al-Abed, Omar; Abdulmonem, Aya; Alhouri, Ahmad; Al Houri, Hasan; Suliman, Alnour; Hassan, Bashar Haj; Hamdan, Alaa; Yu, Ming-Chin; Bouaziz, Hanen; Kchaou, Ali; Tez, Mesut; Kerem, Mustafa; Bayhan, Hüseyin; Aday, Ulaş; Gumusoglu, Alpen; Aydin, Husnu; Hanefa, Fatema; Atici, Ali Emre; Ulgur, Hanife; Sert, Ismail; Atici, Semra Demirli; Colak, Elif; Skoryi, Denys; Kopchak, Kostiantyn; Kvasivka, Oleksandr; Sumarokova, Valeriia; Skipworth, James; Lim, William; Mohamed, Ahmed; Kocher, Hemant; Khalil, Amjad; Carino, Nicola de' Liguori; Gareb, Fahed; Sanjay, Pandanaboyana; Patel, Krishnakumure; Ceresa, Carlo; Russell, Thomas; Mortimer, Matt; Sulciner, Megan; Clancy, Thomas; Nebbia, Martina; Thompson, Rachel; Moris, Dimitrios; Gnerlich, Jennifer; Spencer-Cole, Richard; Krinock, Derek; Osborn, Tamara; Hardgrave, Hailey; Nigh, Joe; Schrope, Beth; Lamm, Ryan; Lavu, Harish; Bowne, Wilbur; Sham, Jonathan; Martins, Paulo; Albar, Aisha; Al-Eryani, Fatima; Al-Saban, Rafat |
| Contributors: |
P. Tinguely; C. Hidalgo Salina; S.M. Staubli; D.A. Rapti; G.K. Fusai; N. Null; M.A. Hilal; C. Bassi; M. Besselink; K. Conlon; B. Davidson; M. Del Chiaro; C. Derveni; M. Falconi; T. Hackert; E. Harrison; S.V. Shrikhande; A. Siriwardena; M. Smith; C. Wolfgang; A. Borakati; D. Balci; N. Machaira; G. Marchegiani; A. Oba; C. Oberkofler; I. Passa; R. Ravikumar; P.S. Velázquez; M. De Santibañe; A.A. Schnitzbauer; F. Soggiu; D. Tamburrino; A. Wei; M. Zachioti; K. Bentabak; S.E. Kacimi; M. Nikfarjam; A. Shcherba; G. Sergeant; G. Coelho; O. Torre; N. Belev; B. Fabrice; E. Tang; J. Martin; C. Diaz; N. Devaud; K. Wei; M. Hendi; D. Mikulic; N. Gouva; A. Nikov; D. Fathallah; M. Saad; O. Tammik; H. Huhta; L. Sulpice; R. Lupinacci; G. Stavrou; E. Felekoura; V. Papazioga; S. Misra; E. Prabowo; H.T. Hashim; M.A. Al-Sader; S. Satoi; K. Obeidat; M. Mohsen; H. Han; M. Khalife; M. Elhadi; A. Dulska; J. Bong; S. Ghani; A.E. Padilla; J. Melchor-Ruan; S. Erdene; A. Benkabbou; P. Nashidengo; J. Koea; A. Adeyeye; O. Alatise; S. Ullah; M.A. Jayyab; S. Amro; W.M. Alnammourah; C. The; M. Pędziwiatr; W. Polkowski; S. Barbu; A. Karamarkovic; D. Galun; B. Goh; B. Trotovšek; J. Omoshoro-Jone; B. Ielpo; A. Abdelmageed |
| Publisher Information: |
Springer |
| Publication Year: |
2025 |
| Collection: |
The University of Milan: Archivio Istituzionale della Ricerca (AIR) |
| Subject Terms: |
Morbidity; Mortality; Pancreas surgery; Pancreatic neoplasm; Pancreatoduodenectomy; Vascular resection; Settore MEDS-06/A - Chirurgia generale |
| Description: |
Background: Pancreatic resection with concomitant vascular resection is increasingly practiced with outcomes mainly reported from specialist centers but lacking results from prospective global data. This study aimed to investigate factors associated with short-term outcomes after vascular resections in pancreatic surgery worldwide. Patients and methods: Data were extracted from a prospective, multicenter, international cross-sectional snapshot study in 2021 (pancreasgroup.org) assessing short-term outcomes after pancreatic surgery worldwide (NCT04652271). In the patient cohort of pancreatic surgery with simultaneous vascular resection for various diseases, short-term outcomes were reported and compared with established benchmark values. Factors affecting major complications, mortality, and histopathological resection status were assessed in multivariable logistic regression analyses with interaction testing. Results: From a total of 3926 patients undergoing pancreatic surgery, 565 had associated vascular resections, of which 444 had venous resections alone and 121 had arterial resections alone or with concomitant venous resection. Of the153 (47%) benchmark cases with pancreatoduodenectomy and venous resection, medianpostoperative morbidity fell within established benchmark criteria. Median90-day major complication and mortality rates were similar in pancreatic resection with venous, arterial orno vascular resections (45and 10%,47 and 6.6%, 42 and 9.6% respectively). Patients undergoing arterial resections that developed a clinically relevant pancreatic fistula faced substantially elevatedodds of 90-day mortality (OR 8.8 CI 1.6-48). In pancreatic ductal adenocarcinoma, the R1 rate was 26%, neoadjuvant chemotherapy being protective for both overall and venous-specific margins. Conclusions: Vascular pancreatic surgery is performed across diverse healthcare settings worldwide. While perioperative complications were comparable to nonvascular pancreatic resections, the observed 90-day mortality was considerable ... |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/40858955; info:eu-repo/semantics/altIdentifier/wos/WOS:001556801200001; firstpage:1; lastpage:12; numberofpages:12; journal:ANNALS OF SURGICAL ONCOLOGY; https://hdl.handle.net/2434/1180715 |
| DOI: |
10.1245/s10434-025-17911-8 |
| Availability: |
https://hdl.handle.net/2434/1180715; https://doi.org/10.1245/s10434-025-17911-8 |
| Rights: |
info:eu-repo/semantics/openAccess ; license:Creative commons ; license uri:http://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.9C181008 |
| Database: |
BASE |