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Cardiovascular Risk and Health Among People With HIV Eligible for Primary Prevention: Insights From the REPRIEVE Trial

Title: Cardiovascular Risk and Health Among People With HIV Eligible for Primary Prevention: Insights From the REPRIEVE Trial
Authors: Douglas, Pamela S.; Umbleja, Triin; Bloomfield, Gerald S.; Fichtenbaum, Carl J.; Zanni, Markella V.; Overton, Edgar T.; Fitch, Kathleen V.; Kileel, Emma M.; Aberg, Judith A.; Currier, Judith; Sponseller, Craig A.; Melbourne, Kathleen; Avihingsanon, Anchalee; Bustorff, Flavio; Estrada, Vicente; Ruxrungtham, Kiat; Saumoy, Maria; Navar, Ann Marie; Hoffmann, Udo; Ribaudo, Heather J.; Grinspoon, Steven; REPRIEVE investigators
Source: Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
Publisher Information: Oxford University Press (OUP)
Publication Year: 2021
Collection: Dipòsit Digital de la Universitat de Barcelona
Subject Terms: VIH (Virus); Malalts de sida; Factors de risc en les malalties; Estils de vida; Malalties cardiovasculars; HIV (Viruses); AIDS patients; Risk factors in diseases; Lifestyles; Cardiovascular diseases
Description: Background: In addition to traditional cardiovascular (CV) risk factors, antiretroviral therapy, lifestyle, and human immunodeficiency virus (HIV)-related factors may contribute to future CV events in persons with HIV (PWH). Methods: Among participants in the global REPRIEVE randomized trial, we characterized demographics and HIV characteristics relative to ACC/AHA pooled cohort equations (PCE) for atherosclerotic CV disease predicted risk and CV health evaluated by Life's Simple 7 (LS7; includes smoking, diet, physical activity, body mass index, blood pressure, total cholesterol, and glucose). Results: Among 7382 REPRIEVE participants (31% women, 45% Black), the median PCE risk score was 4.5% (lower and upper quartiles Q1, Q3: 2.2, 7.2); 29% had a PCE score
Document Type: article in journal/newspaper
File Description: 14 p.; application/pdf
Language: English
Relation: Reproducció del document publicat a: https://doi.org/10.1093/cid/ciab552; Clinical Infectious Diseases, 2021, vol. 73, num. 11, p. 2009-2022; https://doi.org/10.1093/cid/ciab552; https://hdl.handle.net/2445/182347
Availability: https://hdl.handle.net/2445/182347
Rights: cc by-nc-nd (c) Douglas, Pamela S. et al., 2021 ; http://creativecommons.org/licenses/by-nc-nd/3.0/es/ ; info:eu-repo/semantics/openAccess
Accession Number: edsbas.9C64B973
Database: BASE