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Prognostic Value of Red Blood Cell Distribution Width and D-Dimer in Diffuse Large B-cell Lymphoma: Systematic Review and Meta-analysis.

Title: Prognostic Value of Red Blood Cell Distribution Width and D-Dimer in Diffuse Large B-cell Lymphoma: Systematic Review and Meta-analysis.
Authors: Rahchamani, Maryam; Sedghi, Mohammad; Hakimi, Ali; Nejatianfar, Mahdi; Javaheri, Tohid; Tavakoli, Reza; Ahmadi, Ramtin; Azmi-Naei, Nazanin; Kamandi, Neda; Soleimanian, AmirMohammad; Makarem, Mansoureh; Sangani, Saeid Zahmatkesh; Shavaleh, Rasoul; Rahmani, Kazem; Foogerdi, Moloud
Publisher Information: Authorea, Inc.
Publication Year: 2023
Collection: The Winnower (via CrossRef)
Description: Background: The significant role of red blood cell distribution width (RDW) and D-Dimer as prognostic factors in patients with some blood malignancies has been reported recently. Aim: We designed and performed a meta-analysis to investigate the prognostic roles of RDW and D-Dimer in subjects with diffuse large B-cell lymphoma (DLBCL). Materials and Methods: We systematically reviewed PubMed-Medline, SCOPUS, EMBASE, Web of Science Core Collection, and Google Scholar up to 30 April 2023 to look for publications on prognostic effects of RDW and D-Dimer in DLBCL patients. For investigation of the associations between RDW and D-Dimer with the overall survival (OS) and progression-free survival (PFS) of the DLBCL cases, hazard ratio (HR) with 95% confidence intervals (CIs) was used. Results: We included 13 eligible studies in the present meta-analysis. The results of pooled analysis showed that increased levels of RDW was related to poor OS (HR=2.01, 95% CI: 1.62-2.48, P value
Document Type: other/unknown material
Language: unknown
DOI: 10.22541/au.168985458.85923727/v1
Availability: https://doi.org/10.22541/au.168985458.85923727/v1
Accession Number: edsbas.9C7508B5
Database: BASE