| Title: |
P-715. Chronic Conditions as Risk Factors for Respiratory Syncytial Virus-Associated Hospitalization among Community-Dwelling Adults Aged ≥50 Years, 2017 to 2018 |
| Authors: |
Woodruff, Rebecca C; Hamid, Sarah; Pham, Huong; Derado, Gordana; Taylor, Christopher; Sekkarie, Ahlia; Loustalot, Fleetwood; Lundeen, Elizabeth; Kirley, Pam Daily; Austin, Elizabeth; Witt, Lucy S; Ryan, Patricia A; Reeg, Libby; Lynfield, Ruth; Pacheco, Francesca; Keating, Fiona; St George, Katherine; Thomas, Ann; Talbot, Keipp; Hill, Mary; Havers, Fiona P; Melgar, Michael |
| Source: |
Open Forum Infectious Diseases ; volume 12, issue Supplement_1 ; ISSN 2328-8957 |
| Publisher Information: |
Oxford University Press (OUP) |
| Publication Year: |
2025 |
| Description: |
Background In 2023, CDC recommended respiratory syncytial virus (RSV) vaccination for adults aged ≥ 60 years using shared clinical decision-making. Clinical trials of RSV vaccines in younger age groups are ongoing. Identifying chronic conditions associated with increased RSV hospitalization risk can inform vaccination policy.Figure 1.Prevalence of chronic medical conditions among community-dwelling adults aged ≥50 years hospitalized with respiratory syncytial virus (RSV),1 in RSV-NET states,2 and in 50 US states and the District of Columbia2Abbreviations: BMI: body mass index (kg/m2), COPD: chronic obstructive pulmonary disease 1 Prevalence of chronic conditions indicated in the medical record among community-dwelling adults aged ≥50 years hospitalized with laboratory-confirmed RSV infection identified by the RSV Hospitalization Surveillance Network (RSV-NET) from October 2017 to April 2018. 2 Weighted prevalence of community-dwelling adults aged ≥50 years in RSV-NET states (CA, GA, MD, MN, NM, NY, OR, TN) or 50 states and the District of Columbia who self-reported history of chronic medical conditions on the 2018 Behavioral Risk Factor Surveillance System. Methods We compared RSV hospitalization rates among community-dwelling adults aged ≥ 50 years with and without 9 chronic medical conditions in a 38-county catchment area across 8 states. Rate numerators included hospitalizations in adults with and without medical record documentation of each chronic condition, with laboratory-confirmed RSV infection from October 2017 to April 2018 identified by the RSV Hospitalization Surveillance Network (RSV-NET). Rate denominators were catchment area population counts of adults with and without each chronic condition estimated from the 2018 Behavioral Risk Factor Surveillance System, which relies on self-report, and the US Census. Poisson regression using Monte Carlo simulation generated adjusted rate ratios (aRR) and 95% Monte Carlo confidence intervals (CI), adjusted for age, sex, and race and ethnicity ... |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1093/ofid/ofae631.911 |
| Availability: |
https://doi.org/10.1093/ofid/ofae631.911; https://academic.oup.com/ofid/article-pdf/12/Supplement_1/ofae631.911/61677167/ofae631.911.pdf |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.9D279B84 |
| Database: |
BASE |