| Title: |
Carcinoma endometrial: estadiamento e tratamento cirúrgico |
| Authors: |
MAGANHIN LUQUETTI, CAMILLA; Favero, Luiz Francisco Martins; Mendes, Guilherme Vinícius Oliveira; Lemos Neto, Zeuner Pinheiro de; Machado, Mariana Fidelis da Silva; Bezerra, Lívia Caroline de Melo; Lopes, Júlia Bretas Borges; Gonçalves, Bárbara de Araújo; Silva, Altenor Luz Ferreira da; Barros, Carlos Eduardo Ferreira da Costa; Brunacci, Giovana Oliveira; Magalhães, Francine Araújo; Cotrim, Matheus Mendes; Maganhin, Carla Cristina |
| Source: |
Brazilian Journal of Implantology and Health Sciences ; Vol. 6 No. 8 (2024): BJIHS QUALIS B3 - FATOR DE IMPACTO SJIF 5.807; 5393-5403 ; Vol. 6 Núm. 8 (2024): BJIHS QUALIS B3 - FATOR DE IMPACTO SJIF 5.807; 5393-5403 ; v. 6 n. 8 (2024): BJIHS QUALIS B3 - FATOR DE IMPACTO SJIF 5.807; 5393-5403 ; 2674-8169 |
| Publisher Information: |
Editora Brazilian Scientific Publications |
| Publication Year: |
2024 |
| Subject Terms: |
carcinoma endometrial; estadiamento; tratamento; cirúrgico; “endometrial carcinoma”; “surgical treatment”; “diagnosis” e “staging” |
| Description: |
Introduction: Uterine cancer is the most common gynecological malignancy in high-income countries and the second most common in low- and middle-income countries (after cervical cancer). Endometrial adenocarcinoma is the most prevalent histopathological subtype. Its cardinal symptom is abnormal uterine bleeding, and there may be patients with normal findings on cervical cytology. Most are diagnosed when the disease is confined to the uterus, with a 90% 5-year survival rate. The main risk factor is excess endogenous or exogenous estrogen, unopposed by progestin. Lynch syndrome (hereditary non-polyposis colon cancer) is a genetic risk factor; The pathogenesis in these cases is germline mutation in DNA mismatch repair genes. Objectives: to discuss the staging of endometrial cancer, its surgical treatment and its prognostic factors. Methodology: Literature review based on articles from the Scielo, PubMed and VHL databases, from January to March 2024, with the descriptors in English “endometrial carcinoma”, “surgical treatment”, “diagnosis” and “staging”. Complete articles from the last five years (2019-2024) were included, with a total of 30 studies. After reading, studies with other criteria were excluded, choosing 05 full articles. Results and discussion: Before treatment, patients with endometrial carcinoma (EC) should have a complete evaluation, including history (including screening for hereditary susceptibility to cancers, physical examination, and endometrial sampling, to establish the diagnosis of EC. thorax imaging should be performed as part of the initial evaluation to exclude pulmonary metastases. Abdominal and pelvic imaging is rarely performed in patients with nonaggressive SCCs, but is often used to exclude metastases from aggressive SCCs. Bilateral oophorectomy (BSO) and lymphadenectomy. For staging EC in patients with disease apparently confined to the uterus (based on physical examination, with or without pelvic imaging) who are candidates for surgery and in whom it is expected that the procedure ... |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
Portuguese |
| Relation: |
https://bjihs.emnuvens.com.br/bjihs/article/view/3225/3414; https://bjihs.emnuvens.com.br/bjihs/article/view/3225 |
| DOI: |
10.36557/2674-8169.2024v6n8p5393-5403 |
| Availability: |
https://bjihs.emnuvens.com.br/bjihs/article/view/3225; https://doi.org/10.36557/2674-8169.2024v6n8p5393-5403 |
| Rights: |
Copyright (c) 2024 CAMILLA MAGANHIN LUQUETTI, Luiz Francisco Martins Favero, Guilherme Vinícius Oliveira Mendes, Zeuner Pinheiro de Lemos Neto, Mariana Fidelis da Silva Machado, Lívia Caroline de Melo Bezerra, Júlia Bretas Borges Lopes, Bárbara de Araújo Gonçalves, Altenor Luz Ferreira da Silva, Carlos Eduardo Ferreira da Costa Barros, Giovana Oliveira Brunacci, Francine Araújo Magalhães, Matheus Mendes Cotrim, Carla Cristina Maganhin ; https://creativecommons.org/licenses/by/4.0 |
| Accession Number: |
edsbas.9DA4BA45 |
| Database: |
BASE |