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Viral circRNA identification during the course of an adenoviral infection.

Title: Viral circRNA identification during the course of an adenoviral infection.
Authors: Alexis S. Chasseur; Maxime Bellefroid; Mathilde Galais; Meijiao Gong; Pierre Lombard; Sarah Mathieu; Amandine Pecquet; Estelle Plant; Camille Ponsard; Laure Vreux; Carlo Yague-Sanz; Benjamin G. Dewals; Nicolas A. Gillet; Benoît Muylkens; Carine M. Van Lint; Damien Coupeau
Publication Year: 2025
Subject Terms: Medicine; Microbiology; Genetics; Molecular Biology; Evolutionary Biology; Immunology; Infectious Diseases; Virology; Biological Sciences not elsewhere classified; +non%22">xlink "> non; unconventional splicing mechanisms; sanger sequencings validated; recent attention focused; obtained novel insights; initially anticipated due; identify backsplicing events; human pathogens belonging; existing datasets encompassing; conserved eukaryotic patterns; coding rnas play; viral infection cycles; viral genomes include; unique viral characteristics; rna sequencing data; developed bioinformatic tool; various viral families; bioinformatic pipeline tailored; families
Description: The circRNAs were mapped to the hAdV-C5 genome after 12h (A), 18h (B) or 24h (C) of infection. The infection was performed using A549 cells. Relevant ORFs were indicated under the graph on the same scale as the viral genome. The Y axis indicates the abundance of unique circRNAs in reads mapping the backsplice junctions per billion of reads mapping on the viral HAdV-C5 genome. (TIF)
Document Type: still image
Language: unknown
Relation: https://figshare.com/articles/figure/Viral_circRNA_identification_during_the_course_of_an_adenoviral_infection_/30105314
DOI: 10.1371/journal.ppat.1013448.s004
Availability: https://doi.org/10.1371/journal.ppat.1013448.s004; https://figshare.com/articles/figure/Viral_circRNA_identification_during_the_course_of_an_adenoviral_infection_/30105314
Rights: CC BY 4.0
Accession Number: edsbas.9E5F1FC2
Database: BASE