| Title: |
Estimating the burden of iron deficiency among African children |
| Authors: |
Muriuki, JM; Mentzer, AJ; Webb, EL; Morovat, A; Kimita, W; Ndungu, FM; Macharia, AW; Crane, RJ; Berkley, JA; Lule, SA; Cutland, C; Sirima, SB; Diarra, A; Tiono, AB; Bejon, P; Madhi, SA; Hill, AVS; Prentice, AM; Suchdev, PS; Elliott, AM; Williams, TN; Atkinson, S |
| Publisher Information: |
BioMed Central |
| Publication Year: |
2020 |
| Collection: |
Oxford University Research Archive (ORA) |
| Description: |
Background: Iron deficiency (ID) is a major public health burden in African children and accurate prevalence estimates are important for effective nutritional interventions. However, ID may be incorrectly estimated in Africa because most measures of iron status are altered by inflammation and infections such as malaria. Through the current study we have assessed different approaches to the prediction of iron status and estimated the burden of ID in African children. Methods: We assayed iron and inflammatory biomarkers in 4,853 children aged 0–8 years from Kenya, Uganda, Burkina Faso, South Africa, and The Gambia. We described iron status and its relationship with age, sex, inflammation, and malaria parasitemia. We defined ID using the WHO guideline (ferritin |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1186/s12916-020-1502-7 |
| Availability: |
https://doi.org/10.1186/s12916-020-1502-7; https://ora.ox.ac.uk/objects/uuid:5b475220-7409-4cde-8be1-017947fb0820 |
| Rights: |
info:eu-repo/semantics/openAccess ; CC Attribution (CC BY) |
| Accession Number: |
edsbas.9E88DCAB |
| Database: |
BASE |