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Muscle strength, muscle mass and physical impairment in women with hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorder

Title: Muscle strength, muscle mass and physical impairment in women with hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorder
Authors: Coussens, Marie; Lapauw, Bruno; Banica, Thiberiu; De Wandele, Inge; Pacey, Verity; Rombaut, Lies; Malfait, Fransiska; Calders, Patrick
Source: JOURNAL OF MUSCULOSKELETAL & NEURONAL INTERACTIONS ; ISSN: 1108-7161
Publication Year: 2022
Collection: Ghent University Academic Bibliography
Subject Terms: Medicine and Health Sciences; Ehlers-Danlos Syndrome; Hypermobility; Muscle Mass; Muscle Strength; Physical Functioning
Description: Objectives: To evaluate differences in physical impairment, muscle strength, muscle mass and muscle density between patients with hypermobile Ehlers Danlos Syndrome (hEDS), hypermobile spectrum disorder (HSD), and healthy controls. Methods: Female adults with hEDS (n=20) and HSD (n=23), diagnosed to the most recent criteria, and age-matched healthy controls (n=28) completed the Arthritis Impact Measurement Scale (physical functioning) and performed maximal muscle strength and strength endurance tests of lower and upper limbs (hand grip, posture maintenance, 30 seconds chair rise and isokinetic tests). Muscle mass and density were evaluated by dual-energy X-ray absorptiometry and peripheral quantitative computed tomography. Results: No differences in physical functioning and muscle strength were found between adults with hEDS and HSD. Furthermore, no differences in muscle mass and density were observed between the three groups. Nevertheless, when both patient groups were compared to controls, physical functioning, maximal muscle strength and muscle strength endurance were significantly lower (all p
Document Type: article in journal/newspaper
File Description: application/pdf
Language: English
Relation: https://biblio.ugent.be/publication/8744376; https://biblio.ugent.be/publication/8744376/file/8744379
Availability: https://biblio.ugent.be/publication/8744376; https://hdl.handle.net/1854/LU-8744376; https://biblio.ugent.be/publication/8744376/file/8744379
Rights: info:eu-repo/semantics/openAccess
Accession Number: edsbas.A00A92C3
Database: BASE