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To Switch or not to Switch to Long-acting Injectable Cabotegravir/Rilpivirine in PWH With Past Hepatitis B Virus (HBV) Coinfection: Which HBV Markers to Manage Risk of HBV Reactivation?

Title: To Switch or not to Switch to Long-acting Injectable Cabotegravir/Rilpivirine in PWH With Past Hepatitis B Virus (HBV) Coinfection: Which HBV Markers to Manage Risk of HBV Reactivation?
Authors: Ollier, Laurence; De Monte, Anne; Thibault, Vincent; Pugliese, Pascal; Chirio, David; Durant, Jacques; Carles, Michel; Naqvi, Alissa
Source: Open Forum Infectious Diseases ; volume 12, issue 6 ; ISSN 2328-8957
Publisher Information: Oxford University Press (OUP)
Publication Year: 2025
Description: We report the occurrence of low-level hepatitis B virus (HBV) viremia in people with HIV with controlled CD4 counts and isolated core antibody reactivity switched to long-acting injectable cabotegravir/rilpivirine. This series raises questions about the reintroduction of anti-HBV medications, presents the variation of several HBV markers alongside HBV-DNA and reveals an effective spontaneous immune response.
Document Type: article in journal/newspaper
Language: English
DOI: 10.1093/ofid/ofaf266
DOI: 10.1093/ofid/ofaf266/63070532/ofaf266.pdf
Availability: https://doi.org/10.1093/ofid/ofaf266; https://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofaf266/63070532/ofaf266.pdf; https://academic.oup.com/ofid/article-pdf/12/6/ofaf266/63070532/ofaf266.pdf
Rights: https://creativecommons.org/licenses/by-nc-nd/4.0/
Accession Number: edsbas.A07E2E39
Database: BASE