| Title: |
Anomia is present pre-symptomatically in frontotemporal dementia due to MAPT mutations |
| Authors: |
Bouzigues, A; Russell, LL; Peakman, G; Bocchetta, M; Greaves, CV; Convery, RS; Todd, E; Rowe, JB; Borroni, B; Galimberti, D; Tiraboschi, P; Masellis, M; Tartaglia, MC; Finger, E; van Swieten, JC; Seelaar, H; Jiskoot, L; Sorbi, S; Butler, CR; Graff, C; Gerhard, A; Langheinrich, T; Laforce, R; Sanchez-Valle, R; de Mendonça, A |
| Publisher Information: |
Springer |
| Publication Year: |
2026 |
| Collection: |
Oxford University Research Archive (ORA) |
| Description: |
This study suggests the development of early anomia in MAPT mutation carriers, likely to be associated with impaired semantic knowledge. Clinical trials focused on the prodromal period within individuals with MAPT mutations should use language tasks, such as the BNT for patient stratification and as outcome measures. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1007/s00415-022-11068-0 |
| Availability: |
https://doi.org/10.1007/s00415-022-11068-0; https://ora.ox.ac.uk/objects/uuid:0aaafc58-ea39-4bcd-b1f3-06598ab4cb49 |
| Rights: |
info:eu-repo/semantics/openAccess ; CC Attribution (CC BY) |
| Accession Number: |
edsbas.A0BD3385 |
| Database: |
BASE |