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Design and baseline characteristics of the Food4Me study: a web-based randomised controlled trial of personalised nutrition in seven European countries

Title: Design and baseline characteristics of the Food4Me study: a web-based randomised controlled trial of personalised nutrition in seven European countries
Authors: Celis-Morales, Carlos; Livingstone, Katherine M.; Marsaux, Cyril F.M.; Forster, Hannah; O'Donovan, Clare B.; Woolhead, Clara; Macready, Anna L.; Fallaize, Rosalind; Navas-Carretero, Santiago; San-Cristobal, Rodrigo; Kolossa, Silvia; Hartwig, Kai; Tsirigoti, Lydia; Lambrinou, Christina P.; Moschonis, George; Godlewska, Magdalena; Surwiłło, Agnieszka; Grimaldi, Keith; Bouwman, Jildau; Daly, E.J.; Akujobi, Victor; O'Riordan, Rick; Hoonhout, Jettie; Claassen, Arjan; Hoeller, Ulrich; Gundersen, Thomas E.; Kaland, Siv E.; Matthews, John N.S.; Manios, Yannis; Traczyk, Iwona; Drevon, Christian A.; Gibney, Eileen R.; Brennan, Lorraine; Walsh, Marianne C.; Lovegrove, Julie A.; Alfredo Martinez, J.; Saris, Wim H.M.; Daniel, Hannelore; Gibney, Mike; Mathers, John C.
Publisher Information: Springer Berlin Heidelberg
Publication Year: 2015
Collection: University of Glasgow: Enlighten - Publications
Description: Improving lifestyle behaviours has considerable potential for reducing the global burden of non-communicable diseases, promoting better health across the life-course and increasing well-being. However, realising this potential will require the development, testing and implementation of much more effective behaviour change interventions than are used conventionally. Therefore, the aim of this study was to conduct a multi-centre, web-based, proof-of-principle study of personalised nutrition (PN) to determine whether providing more personalised dietary advice leads to greater improvements in eating patterns and health outcomes compared to conventional population-based advice. A total of 5,562 volunteers were screened across seven European countries; the first 1,607 participants who fulfilled the inclusion criteria were recruited into the trial. Participants were randomly assigned to one of the following intervention groups for a 6-month period: Level 0-control group-receiving conventional, non-PN advice; Level 1-receiving PN advice based on dietary intake data alone; Level 2-receiving PN advice based on dietary intake and phenotypic data; and Level 3-receiving PN advice based on dietary intake, phenotypic and genotypic data. A total of 1,607 participants had a mean age of 39.8 years (ranging from 18 to 79 years). Of these participants, 60.9 % were women and 96.7 % were from white-European background. The mean BMI for all randomised participants was 25.5 kg m(-2), and 44.8 % of the participants had a BMI ≥ 25.0 kg m(-2). Food4Me is the first large multi-centre RCT of web-based PN. The main outcomes from the Food4Me study will be submitted for publication during 2015.
Document Type: article in journal/newspaper
Language: unknown
Relation: Celis-Morales, C. et al. (2015) Design and baseline characteristics of the Food4Me study: a web-based randomised controlled trial of personalised nutrition in seven European countries. Genes and Nutrition , 10(1), 450. (doi:10.1007/s12263-014-0450-2 ) (PMID:25491748) (PMCID:PMC4261071)
Availability: https://eprints.gla.ac.uk/104734/
Accession Number: edsbas.A20D5E77
Database: BASE