| Title: |
804 WOLF PARKINSON WHITE SYNDROME OR ASYMPTOMATIC VENTRICULAR PRE-EXITATION IN CHILDREN: EVALUATION OF ELECTROPHYSIOLOGICAL PROPERTIES CHANGES IN TWO DIFFERENT TIMING |
| Authors: |
Raimondo, Cristina; Garibaldi, Silvia; Quintilio Alberio, Antonino Maria; Cazzoli, Ilaria; Stefano Silvetti, Massimo; Pazzano, Vincenzo; Tamburri, Ilaria; Drago, Fabrizio |
| Source: |
European Heart Journal Supplements ; volume 24, issue Supplement_K ; ISSN 1520-765X 1554-2815 |
| Publisher Information: |
Oxford University Press (OUP) |
| Publication Year: |
2022 |
| Description: |
Background In patients with Wolf Parkinson White (WPW) syndrome or asymptomatic ventricular pre-excitation (VP), electrophysiologic study (EPS) is recommended to assess and to stratify the risk of life - threatening arrhythmias and SCD. However, little information exist on the timing of EPS study. In particular, the electrophysiological properties variations of accessory pathway (AP) in patients with asymptomatic or symptomatic VP remain to be defined. Recently, the evolution of electrophysiological data was observed in a cohort of patients by including children and adults, although a transcatheter ablation (TCA) was performed during the evaluation among the two EPS. According to our knowledge, no study exists related to the changes over time in the conductive properties of an atrioventricular accessory pathway (AP) and arrhythmic vulnerability in the pediatric - young adult population. Aims The aim of our study was to investigate the evolution of clinical and electrophysiological datas of the manifest PV (intermittent or persistent), the arrhythmic vulnerability and any modifications in the features of AP anterograde conduction in symptomatic or asymptomatic children, examined on two separate timing, at least 2 years apart from one EPS to the next. Method This is a retrospective monocentric observational study performed at Bambino Gesu` Children's Hospital, Rome, Italy. Between January 2011 and July 2022, we enrolled forty-four children and young adults (32 male, mean age 10 years± 2,42) with manifest ventricular preexcitation underwent, as our standard management, at two electrophysiolgical studies (EPS, transesophageal and/or endocavitary), both at rest and during adrenergic stress (exercise testing or isoproterenol infusion) in two different timing (T0 and T1) within a minimal interval of 2 year. No transchateter ablation was performed between two EPS. Clinical and electrophysiological data were collected and compared. Results We observed a significant modification in atrioventricular accessory ... |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1093/eurheartjsupp/suac121.070 |
| Availability: |
https://doi.org/10.1093/eurheartjsupp/suac121.070; https://academic.oup.com/eurheartjsupp/article-pdf/24/Supplement_K/suac121.070/47965602/suac121.070.pdf |
| Rights: |
https://academic.oup.com/pages/standard-publication-reuse-rights |
| Accession Number: |
edsbas.A2DD1333 |
| Database: |
BASE |