| Title: |
Development and validation of prediction models for fetal growth restriction and birthweight : an individual participant data meta-analysis |
| Authors: |
Allotey, John; Archer, Lucinda; Coomar, Dyuti; Snell, Kym Ie; Smuk, Melanie; Oakey, Lucy; Haqnawaz, Sadia; Betrán, Ana Pilar; Chappell, Lucy C.; Ganzevoort, Wessel; Gordijn, Sanne; Khalil, Asma; Mol, Ben W.; Morris, Rachel K.; Myers, Jenny; Papageorghiou, Aris T.; Thilaganathan, Basky; Da Silva Costa, Fabricio; Facchinetti, Fabio; Coomarasamy, Arri; Ohkuchi, Akihide; Eskild, Anne; Arenas Ramírez, Javier; Galindo, Alberto; Herraiz, Ignacio; Prefumo, Federico; Saito, Shigeru; Sletner, Line; Cecatti, Jose Guilherme; Gabbay-Benziv, Rinat; Goffinet, Francois; Baschat, Ahmet A.; Souza, Renato T.; Mone, Fionnuala; Farrar, Diane; Heinonen, Seppo; Salvesen, Kjell; Smits, Luc Jm; Bhattacharya, Sohinee; Nagata, Chie; Takeda, Satoru; van Gelder, Marleen Mhj; Anggraini, Dewi; Yeo, Seon Ae; West, Jane; Zamora, Javier; Mistry, Hema; Riley, Richard D.; Thangaratinam, Shakila |
| Contributors: |
HUS Gynecology and Obstetrics; Department of Obstetrics and Gynecology; University of Helsinki |
| Publisher Information: |
NIHR Journals Library |
| Publication Year: |
2025 |
| Collection: |
Helsingfors Universitet: HELDA – Helsingin yliopiston digitaalinen arkisto |
| Subject Terms: |
INDIVIDUAL PARTICIPANTDATA; FETAL GROWTH RESTRICTION; EXTERNAL VALIDATION; PREDICTION MODEL; BIRTHWEIGHT; ECONOMIC EVALUATION; PROGNOSTIC MODEL; Gynaecology and paediatrics |
| Description: |
Background: Fetal growth restriction is associated with perinatal morbidity and mortality. Early identification of women having at-risk fetuses can reduce perinatal adverse outcomes. Objectives: To assess the predictive performance of existing models predicting fetal growth restriction and birthweight, and if needed, to develop and validate new multivariable models using individual participant data. Design: Individual participant data meta-analyses of cohorts in International Prediction of Pregnancy Complications network, decision curve analysis and health economics analysis. Participants: Pregnant women at booking. External validation of existing models (9 cohorts, 441,415 pregnancies); International Prediction of Pregnancy Complications model development and validation (4 cohorts, 237,228 pregnancies). Predictors: Maternal clinical characteristics, biochemical and ultrasound markers. Primary outcomes: fetal growth restriction defined as birthweight |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| ISBN: |
978-85-203-7827-4; 85-203-7827-7 |
| ISSN: |
39252507 |
| Relation: |
This award was funded by the National Institute for Health and Care Research (NIHR) Health Technology Assessment programme (NIHR award ref: 17/148/07) and is published in full in Health Technology Assessment; Vol. 28, No. 47. See the NIHR Funding and Awards website for further award information.; https://hdl.handle.net/10138/591430; 85203782779; 001330586500001 |
| Availability: |
https://hdl.handle.net/10138/591430 |
| Rights: |
cc_by ; info:eu-repo/semantics/openAccess ; openAccess |
| Accession Number: |
edsbas.A3ADC215 |
| Database: |
BASE |