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Design and Baseline Characteristics of the Finerenone in Reducing Cardiovascular Mortality and Morbidity in Diabetic Kidney Disease Trial

Title:	Design and Baseline Characteristics of the Finerenone in Reducing Cardiovascular Mortality and Morbidity in Diabetic Kidney Disease Trial
Authors:	Ruilope, Luis M; Agarwal, Rajiv; Anker, Stefan D; Bakris, George L; Filippatos, Gerasimos; Nowack, Christina; Kolkhof, Peter; Joseph, Amer; Mentenich, Nicole; Pitt, Bertram; Diego Besada; Alfredo Wassermann; Julio Bittar; Alicia Elbert; Augusto Vallejos; Gloria Viñes; Hugo Sanabria; Federico Pérez Manghi; Alberto Liberman; Inés Bartolacci; Diego Aizenberg; Mariano Chahin; Laura Maffei; Elizabeth Gelersztein; Bernhard Ludvik; Hans-Robert Schönherr; Heinz Drexel; Wolfgang Preiß; Ursula Hanusch; Peter Neudorfer; Friedrich Prischl; Bernhard Paulweber; Christoph Ebenbichler; Rudolf Prager; Harald Sourij; Gerit-Holger Schernthaner; Martin Clodi; Evelyn Fliesser-Görzer; Elif Ekinci; Richard MacIsaac; David Packham; Hugo Stephenson; Michael Suranyi; Gary Wittert; Katie-Jane Wynne; Alexia Pape; Duncan Topliss; Peter Colman; Craig Nelson; James Vandeleur; David Colquhoun; Simon Roger; Peak Mann Mah; Walter Abhayaratna; Luc VAN Gaal; Pieter Gillard; Jean-Michel Hougardy; Marijn Speeckaert; Koen Stas; Wendy Engelen; Francis Duyck; André Scheen; Hilde Vanbelleghem; Peter Doubel; Svetla Vasileva; Rosen Rashkov; Boyan Nonchev; Theodora Temelkova-Kurktschieva; Mariana Yoncheva-Mihaylova; Rangel Rangelov; Neli Klyuchkova; Pavel Stanchev; Zhivko Tagarev; Radostina Boshnyashka; Petya Manova; Zhulieta Prakova; Mariya Lucheva; Valentina Gushterova; Ghassan Farah; Dimitar Georgiev; Mariyana Pichmanova; Dotska Minkova; Bilyana Stoyanovska-Elencheva; Maria Eugenia Canziani; Miguel Hissa; Irene Noronha; Joao Eduardo Salles; Daniela Antunes; Freddy Eliaschewitz; Carlos Eduardo Figueiredo; Rogerio de Paula; Luis Canani; Maurilo Leite Jr; Bruno Paolino; Rosangela Rea; Sergio Vencio; Claudia Brito; Raphael Paschoalin; Roberto Pecoits Filho; Eduardo Vasconcellos; Nathalia Paschoalin; Adriana Forti; Roberto Botelho; Miguel Riella; Dalton Precoma; Maria Cerqueira; Lilia Maia; Evandro Portes; Marcio Pereira; Joanne Liutkus; Dennis O Keefe; Richard Tytus; Brian Carlson; James Conway; Michael Walsh; Igor Wilderman; Andrew Steele; Sheldon Tobe; Louise Vitou; Karthik Tennankore; Valdemar Martinho; Philip McFarlane; Daniel Shu; Serge Cournoyer; Richard Dumas; Giuseppe Mazza; Guy Tellier; George Tsoukas; Stanley Weisnagel; Jean-Francois Yale; Sameh Fikry; Randolph Hart; Pavel Hamet; Francois Madore; Paul Barre; Daniel Schwartz; Allan Kelly; Ivor Teitelbaum; Sean Peterson; Sam Henein; Richard Goluch; Gregoire Wuerzner; Markus Laimer; Stefan Bilz; Marc Donath; Gottfried Rudofsky; Christopher Strey; Antoinette Pechère-Bertschi; Paola Varleta; Fernando González; Marcelo Medina; Carmen Romero; Victor Saavedra; Juan Carlos Prieto; Eliana Reyes; Juan Carlos Palma; Jorge Cobos; Zhihong Liu; Dalong Zhu; Nan Chen; Fang Liu; Li Wang; Qing Su; Bingyin Shi; Aiping Yin; Hao Wang; Yan Li; Jianying Niu; Chaoqing Wu; Xinjun Wang; Ying Zhang; Ai Peng; Jianhua Ma; Yuxiu Li; Hongguang Zheng; Minxiang Lei; Zhaohui Mo; Nanwei Tong; Jinluo Cheng; Youping Dong; Xudong Xu; Qinkai Chen; Tianjun Guan; Gang Long; Changying Xing; Ling Li; Yinghong Liu; Hao Zhang; Ling Zhong; Zhonghe Li; Longyi Zeng; Jiali Wei; Hanqing Cai; Tianfeng Wu; Weiping Lu; Ning Xu; Yibing Lu; Dejun Chen; Ruifang Bu; Jiansong Shen; Junwu Dong; Zhiquan Zhao; Fei Xiong; Fangfang Jiang; Jinkui Yang; Jian Kuang; Guoyuan Lu; Lihua Wang; Yanlin Zhang; Shuifu Tang; Weiying Guo; Jian Liu; Sheng Jiang; Yi Fang; Yuming Du; Zhuxing Sun; Yuantao Liu; Liyong Zhong; Dongmei Li; Hongmei Li; Chuanming Hao; Feixia Shen; Jianqin Wang; Jingmei Li; Dora Molina; Carlos Cure; Jaime Ibarra; Gustavo Aroca; Hernán Yupanqui; Eric Hernández; Mónica López; Gregorio Sánchez; Germán Barreto; Edgar Arcos; Miguel Urina; William Kattah; Carlos Durán; Clara Arango; Julian Coronel; Guillermo Blanco; Mónica Terront; Gustavo Guzmán; Luis García; Carlos Jaramillo; Manuel Liévano; Diego Benitez; Tatiana Cárdenas; Iván Villegas; Sandra Barrera; Nicolás Jaramillo; Rodrigo Botero; Nelly Beltrán López; Freddy Trujillo; Martin Prazny; Jitka Hasalova Zapletalova; Libor Okenka; Dino Alferi; Tomas Edelsberger; Pavel Tomanek; Jiri Brezina; Olga Hola; Jana Houdova; Petr Bucek; David Karasek; Sarka Kopecka; Richard Kovar; Michal Brada; Lucie Hornova; Eva Krcova; Hana Lubanda; Vlasta Kutejova; Jiri Kuchar; Helena Hrmova; Jiri Pumprla; Magdalena Mokrejsova; Drahomira Gulakova; Ivo Matyasek; Thilo Krüger; Hermann Haller; Thorsten Koch; Ludger Rose; Diethelm Tschöpe; Lutz Stemler; Volker Schettler; Andreas Pfützner; Karl Derwahl; Thomas Horacek; Helena Sigal; Heidrun Täschner; Ingolf Schiefke; Andreas Hagenow; Andreas Birkenfeld; Christoph Axthelm; Christoph Wanner; Klaus Busch; Heike Schlichthaar; Christoph Hasslacher; Stefan Degenhardt; Markus van der Giet; Georg Strack; Norbert Schöll; Bernhard R Winkelmann; Lars Rump; Ruth Nischik; Bernd Schröppel; Thomas Giebel; Achim Ulmer; Andrea Rinke; Christel Contzen; Wolfgang Jungmair; Nicole Toursarkissian; Christof Kloos; Joachim Müller; Thomas Schürholz; Hermann Braun; Frank Pistrosch; Per Poulsen; Claus Juhl; Joan Nielsen; Jesper Bech; Ole Rasmussen; Peter Rossing; Jens Faber; Thure Krarup; Morten Lindhardt; Ulrik Pedersen-Bjergaard Pedersen-Bjergaard; Karoline Schousboe; Jørgen Hangaard; Sten Madsbad; Gunnar Gislason; Grzegorz Jaroslaw Pacyk; Olga González Albarrán; Carlos Sánchez Juan; José Julián Segura de la Morena; Secundino Cigarrán Guldris; Francisco Martínez Deben; José María Pascual Izuel; Julio Pascual Santos; Francesca Calero; Alfonso Soto; Manuel Polaina Rusillo; Josep Redón; Josep Galcerán; Juan Mediavilla; Ma Dolores Martínez Esteban; Alfredo Michán; Fernando de Álvaro; Javier Escalada San Martín; Josep Cruzado Garrit; Cristina Castro; Fernando Cereto Castro; Rafael Santamaría Olmo; Esteban Poch; Judith Martins; Julio Hernández Jaras; Meritxell Ibernón; Daniel Seron; Hanane Bouarich; Maribel Troya; Jorma Strand; Ilkka Kantola; Sakari Nieminen; Arvo Koistinen; Kristiina Kananen; Sakari Sulosaari; Mikko Honkasalo; Pirkko Korsoff; Tuomo Nieminen; Karita Sadeharju; Kari Humaloja; Jorma Lahtela; Philippe Zaoui; Jean-Pierre Fauvel; Ronan Roussel; Didier Gouet; Pierre Serusclat; Sylvaine Clavel; Bruno Guerci; Bruno Verges; Olivier Moranne; Arnaud Monier; Alexandre Klein; François Chantrel; Yannick LE Meur; Rafik Mesbah; Bertrand Cariou; Dominique Guerrot; Karim Gallouj; Kieran McCafferty; Arutchelvam Vijayaraman; Yuk-Ki Wong; Dhanya Kalathil; Sam Rice; Sui Phi Kon; Hassan Kahal; Cuong Dang; Fahmy Hanna; Christina Kyriakidou; Imrozia Arif; Anne Kilvert; Pauline Swift; Ioannis Stefanidis; Ploumis Passadakis; Aikaterini Papagianni; Erifili Hatziagelaki; Dorothea Papadopoulou; Ioannis Boletis; Ioanna Makriniotou; Theodora Kounadi; Ioannis Ioannidis; Paul Lee; Ching Wan Ronald Ma; Vincent Yeung; Tai Pang Ip; Ebrahim Noori; Julianna Kiss; Eleonora Harcsa; Albert Szocs; Szilard Vasas; Krisztina Wudi; Robert Kirschner; Dora Bajcsi; Beata Lamboy; Botond Literati-Nagy; Gabor Nyirati; Gizella Petro; Karoly Schneider; Katalin Keltai; Akos Kalina; Peter Danos; Szilvia Kazup; Zsolt Zilahi; Judit Simon; Laszlo Kovacs; Marianna Zsom; Margit Mileder; Laszlo Nagy; Yoram Yagil; Julio Wainstein; Ofri Mosenzon; Rosane Abramof Ness; Sydney Ben Chetrit; Faiad Adawi; Idit Liberty; Ehud Grossman; Mazen Elias; Zaher Armaly; Evgeny Farber; Assy Nimer; Amir Bashkin; Gil Chernin; Shai Efrati; Doron Schwartz; Noa Berar Yanay; Mariela Glandt; Robert Zukermann; Majdi Halabi; Shaul Atar; Mahmud Darawsha; Norberto Perico; Gaetano La Manna; Giovanni Giorgio Battaglia; Domenico Santoro; PierMarco Piatti; Enzo Bonora; Davide Carlo Maggi; Paolo Calabrò; Roberto Cimino; Roberto Trevisan; Paolo Fiorina; Antonio Pisani; Antonello Pani; Gennaro Santorelli; Carlo Antonio Bossi; Giancarlo Tonolo; Enrico Fiaccadori; Anna Maria Veronelli; Michele Emdin; Paola Ponzani; Maria Cristina Gregorini; Franco Luigi Cavalot; Carlo Bruno Giorda; Taro Shibasaki; Akihiro Hamasaki; Takashi Nomiyama; Sunao Matsubayashi; Junji Shinoda; Kazunari Matsumoto; Hideo Kanehara; Yoshihide Hirohata; Masayo Yamada; Jun Nakazawa; Yoshimitsu Yamasaki; Mikihiro Nakayama; Ryuichi Furuya; Osamu Ebisui; Satsuki Kawasaki; Daishiro Yamada; Masayuki Noritake; Tamayo Ishiko; Nobuhiro Sasaki; Daisuke Suzuki; Asami Tanaka; Miyuki Kubota; Hideo Araki; Hiroshi Ohashi; Takeshi Osonoi; Kazuo Yamagata; Naruhiro Fujita; Daisuke Kanda; Seiichi Tanaka; Junko Koide; Masao Ishii; Takayuki Ogiwara; Masaaki Suzuki; Taiji Sekigami; Takayuki Higashi; Yuko Yambe; Yoshiro Kusano; Hidetoshi Kikuchi; Hiroaki Miyaoka; Kiyoe Kato; Masayuki Kashima; Fumiko Yamakawa; Shuji Horinouchi; Hirofumi Imoto; Hiroshi Sobajima; Hidetoshi Kanai; Naoki Matsuoka; Hirotaka Shibata; Akemi Inagaki; Toshiyuki Sugiura; Toru Sugiyama; Hidekatsu Yanai; Yoshiyuki Hamamoto; Masahiro Hatazaki; Terumasa Hayashi; Kunihisa Kobayashi; Satoshi Murao; Makoto Ujihara; Kazuya Sugitatsu; Katsunori Kawamitsu; Ken Yamakawa; Izumi Tsunematsu; Fumi Kikuchi; Hideaki Jinnouchi; Tetsuyuki Yasuda; Hajime Maeda; Yasuto Matsuo; Hideki Okamoto; Takeshi Katsuki; Ken Yajima; Takeshi Morita; Masayuki Inagaki; WooJe Lee; JunGoo Kang; Cheol Young Park; HyeSoon Kim; SinGon Kim; YouCheol Hwang; InJoo Kim; JaeHyeon Kim; Young Min Cho; ByungWan Lee; ChoonHee Chung; Soo Lim; Jae Myung Yu; Dovile Kriauciuniene; Antanas Navickas; Audrone Velaviciene; Egle Urbanaviciene; Gediminas Urbonas; Jurate Lasiene; Lina Radzeviciene; Ron Gansevoort; Adriaan Kooy; A G Lieverse; E L Penne; Ruud J M van Leendert; M van Buren; A H Boonstra; R C Bakker; Marielle Krekels; C B Brouwer; P T Luik; J N M Barendregt; Bert-Jan van den Born; Trine Finnes; Thomas Karlsson; Hilde Selsås; Emil Asprusten; Robert Hagemeier; Erik Eriksen; Knut Risberg; Hans Høivik; Leidulv Solnør; Frode Thorup; Jan Rocke; Rick Cutfield; Peter Dunn; Jeremy Krebs; Russell Scott; Kingsley Nirmalaraj; Nine Smuts; John Baker; Veronica Crawford; Albert Bautista; Roberto Mirasol; Elizabeth Catindig; Glenda Pamugas; Louie Tirador; Maribel Tanque; Janusz Gumprecht; Piotr Napora; Edward Franek; Andrzej Stankiewicz; Katarzyna Landa; Agnieszka Tiuryn-Petrulewicz; Kazimierz Ciechanowski; Bogna Wierusz-Wysocka; Barbara Rewerska; Grazyna Cieslik; Michal Hoffmann; Michal Nowicki; Jolanta Krzykowska; Stanislaw Mazur; Katarzyna Wasilewska; Anna Ocicka-Kozakiewicz; Ewa Skokowska; Renata Wnetrzak-Michalska; Jan Ruxer; Patrycja Butrymowicz; Katarzyna Madziarska; Ilona Kurnatowska; Teresa Rusicka; Adam Madrzejewski; Tomasz Stompor; Jose Guia; Amalia Pereira; Pedro Melo; Cristina Roque; Francisco Rosario; Fernando Teixeira E Costa; Fernando Nolasco; Edgar Almeida; Pedro Matos; Cesar Esteves; Rui Carvalho; Ilidio Brandao; Susana Heitor; Ana Vila Lobos; Rosa Ballesteros; Gil Silva; Carlos Barreto; Ana Silva; Natalya Vorokhobina; Alexander Sherenkov; Ivan Gordeev; Olga Semenova; Sergey Levashov; Vyacheslav Marasaev; Ruslan Sardinov; Vadim Klimontov; Vitaliy Baranov; Nadezhda Verlan; Albert Galyavich; Arkadiy Demko; Zhanna Kobalava; Elena Zakharova; Lyudmila Kvitkova; Oleg Solovev; Elena Smolyarchuk; Larisa Zhukova; Elena Zhdanova; Andrey Babkin; Galina Nechaeva; Olga Barbarash; Elena Rechkova; Roman Libis; Elena Kosmacheva; Tatyana Rodionova; Irina Ipatko; Alexander Dreval; Nina Petunina; Elena Chernyavskaya; Alsu Zalevskaya; Yuriy Khalimov; Tatyana Zykova; Anton Edin; Ashot Mkrtumyan; Shamil Palyutin; Vyacheslav Mareev; Leonid Strongin; Olga Ukhanova; Mikhail Antsiferov; Davyd Yakhontov; Leonid Pimenov; Natalya Koziolova; Konstantin Nikolaev; Imad Merai; Olga Zanozina; Leyla Gaysina; Mikhail Arkhipov; Natalia Malykh; Oksana Rymar; Vladimir Martynenko; Sofya Malyutina; Polina Ermakova; Marina Kalashnikova; Bengt-Olov Tengmark; Carl-Johan Lindholm; Dan Curiac; Ken Eliasson; Erik Rein-Hedin; Gregor Guron; Inga Soveri; Annette Bruchfeld; Jonas Spaak; Malin Frank; Magnus Löndahl; Hans Larnefeldt; Margareta Hellgren; Olof Hellberg; Yong Mong Bee; Chee Fang Sum; Ru San Tan; Piyamitr Sritara; Chaicharn Deerochanawong; Chatlert Pongchaiyakul; Natapong Kosachunhanan; Bancha Satirapoj; Ahmet Temizhan; Ibrahim Gul; Ramazan Sari; Aytekin Oguz; Mustafa Tigen; Huseyin Yilmaz; Ozer Badak; Oner Ozdogan; Talat Tavli; Necmi Eren; Murat Cayli; Sedat Ustundag; Yavuz Yenicerioglu; Ismail Kocyigit; Abdulbaki Kumbasar; Idris Sahin; Lee-Ming Chuang; Ju-Ying Jiang; Chien-Te Lee; Der-Cherng Tarng; Shih-Te Tu; Mai-Szu Wu; Ming-Ju Wu; Chiz-Tzung Chang; Cheng-Chieh Hung; Liubov Sokolova; Borys Mankovsky; Dmytro Kogut; Viktoriia Chernikova; Kateryna Malyar; Nonna Kravchun; Volodymyr Botsyurko; Vitaliy Maslyanko; Liliya Martynyuk; Oleksandr Serhiyenko; Vasyl Stryzhak; Halyna Myshanych; Oleksandra Donets; Iryna Bondarets; Maryna Vlasenko; Nataliia Pertseva; Mariia Grachova; Ivan Smirnov; Larysa Pererva; Ivan Fushtey; Julia Komisarenko; Anna Isayeva; Carl Meisner; Bobby Khan; Louis Maletz; Bradley Dixon; Ahmed Arif; Timothy Jackson; Mirela Ponduchi; Mahfouz El Shahawy; Salil Nadkarni; Daniel Urbach; Jorge Paoli-Bruno; Henry Lora; Umar Farooq; Steven Zeig; Lance Rudolph; Nabil Andrawis; William Kaye; Jill Meyer; Khalid Bashir; Glenn Heigerick; James Smelser; Javier Ricardo Colomar; David Scott; Brian First; Stuart Handelsman; Jose Bautista; Rajesh Patel; Stephen Minton; Juan Frias; Luis Ramos-Gonez; John Bertsch; Ali Iranmanesh; Vivian Fonseca; Michael Yuryev; Larry Popeil; Jose Cardona; Sanjeev Saxena; Santosh Sharma; Edgar Gonzalez; Richard Solomon; Muhammad Khan; Ahmed Awad; David Fitz-Patrick; Douglas Linfert; David Grant; Susan Brian; Leon Fogelfeld; Rafael Canadas; Pablo Pergola; Joseph Soufer; Rakesh Patel; Shujauddin Valika; Jonathan Winston; D Allison; Maria Caramori; Stanley Koch; Anjay Rastogi; Jonathan Bornfreund; Michael Rocco; Maxine Hamilton; Luis Garcia-Mayol; Peter Weissman; Suzanne Oparil; Gary Ruoff; Kyaw Soe; Gary Korff; Robert Busch; Alexander Lurie; Israel Hartman; Garfield Samuels; Derek LeJeune; Visal Numrungroad; Stephen Brietzke; Zeid Kayali; Harold Szerlip; Steven Barag; Gilberto Seco; Damaris Vega; Osvaldo Brusco; Camil Kreit; Humberto Cruz; Bharat Mocherla; Sharma Prabhakar; George Fadda; Martin Valdes; Eugene Soroka; Ramin Berenji; Sreedhara Alla; Shweta Bansal; A Odugbesan; Karlton Pettis; Masoud Azizad; Idalia Acosta; Atoya Adams; William Sanchez; Rosa Suarez; Efrain Reisin; Carlos Herrera; Keung Lee; Csaba Kovesdy; Adam Whaley-Connell; Aldo Peixoto; Ronald Mayfield; Mahendra Jain; Earl Martin; Paul Norwood; Jonathan Wise; Hugo Romeu; Stephen Halpern; Mustafa Mandviwala; Thomas Turk; Anna Burgner; David Bleich; Ankur Doshi; Jose Carpio; Jorge Posada; Alexander Magno; Samer Nakhle; Gary Goldstein; Caroline Mbogua; Dierdre McMullen; Dilawar Ajani; Wayne Kotzker; Nelson Kopyt; Richard Treger; Yusuf Ruhullah; Sharon Adler; Harjeet Brar; Marc Rendell; Dennis Ross; Srinivasan Beddhu; German Hernandez; Sylvia Rosas; M Sue Kirkman; Mohammed El-Shahawy; Jeffrey Rothman; Ahmad Barakzoy; Aparna Tamirisa; Sabrina Benjamin; Michael Bahrami; Prabir Roy-Chaudhury; Ramprasad Dandillaya; Gretel Trullenque; Jose Birriel; John Flack; Karen Johnson; Brenda Lemus; Guillermo Umpierrez; Geetha Maddukuri; Kenneth Jamerson; Christopher Case; Patrick Fluck; Saeed Kronfli; Violet Habwe; Bala Subramanian; Tariq Shafi; Rupesh Raina; Roland Fernando; Sourabh Kharait; Carlos Hernandez-Cassis; Raymond Fink; Jamal Hammoud; Amer Al-Karadsheh; Manuel Montero; Philip Nicol; Jesus Navarro; Michael Shanik; Zia Din; Francisco Gonzalez-Abreu; Sam Lerman; Claude Galphin; John Evans; Ashwini Gore; Radica Alicic; Mandeep Sahani; Roberto Pisoni; Tuan-Huy Tran; Jeffrey Ryu; Harvey Serota; Nilda Neyra; Richard O Donovan; Sreedhar Mandayam; Moustafa Moustafa; Mark Smith; Arvind Krishna; Arjun Sinha; Anuj Bhargava; Kodangudi Ramanathan; Soni Dhanireddy; Stephen Thomson; Romanita Nica; Emaad Abdel-Rahman; Mark Barney; Mariana Markell; Nauman Shahid; David Oliver; Tran Khanh; Pham Nguyen Son; Lam VAN Hoang; Boi Ngoc Nguyen; Nguyen Minh Nui; Lan Phuong Tran; Fayzal Ahmed; Dorothea Urbach; Dirkie Jansen van Rensburg; Gracjan Podgorski; Aslam Amod; Sindeep Bhana; Shaifali Joshi; Essack Mitha; Deepak Lakha; Louis van Zyl; J Trokis; Naresh Ranjith; Mary Seeber; Mohamed Sarvan; Mohammed Tayob; Brian Rayner; Larry Distiller; Heidi Siebert; Mukesh Joshi; Paul Rheeder; Magdalena Madero Rovalo; Gustavo Solache Ortiz; Gustavo Méndez Machado; Rafael Valdez Ortiz; Juan Villagordoa Mesa; Saúl Irizar Santana; Sandro Avila Pardo; Jorge Escobedo de la Peña; Guillermo González Gálvez; Leobardo Sauque Reyna; Miriam Bastidas Adrian; Guillermo Fanghänel Salmón; Ramiro Gutiérrez Ochoa; Luis Nevarez Ruiz; Gabriel Ramos López; Alfredo Chew Wong; Arturo Saldaña Mendoza; Pedro García Hernández; José González González; Melchor Alpizar Salazar; José Lazcano Soto; Amaury Roman-Miranda; Gregorio Cortes-Maisonet; Liana Turcu; Adriana Dumitrescu; Gabriela Radulian; Hortensia Barbonta; Cristina Mistodie; Georgeta Vacaru; Alexandrina Popescu; Adrian Vlad; Silvia Paveliu; Nicoleta Mindrescu; Adrian Albota; Ella Pintilei; Lavinia Pop; Gabriela Negrisanu; Doina Catrinoiu; Cornelia Bala; Amorin Popa; Iosif Szilagyi; Ciprian Constantin; Elena Caceaune; Adriana Onaca; Li Yuan Lee; Nor Azizah Aziz; Wan Mohd Izani Wan Mohamed; Wan Hasnul Halimi Bin Wan Hasan; Jeyakantha Ratnasingam; Nik Nur Fatnoon Nik Ahmad; Rizmy Najme Khir; Norhaliza Mohd Ali; Masni Mohamad; Chek Loong Loh; Joe Eustace; John Holian; Donal Reddan; Yvonne O Meara; Mensud Hatunic; Zuzana Ochodnicka; Dalibor Sosovec; Andrej Dzupina; Ingrid Buganova; Jana Babikova; Denisa Spodniakova
Contributors:	Luis M, Ruilope; Rajiv, Agarwal; Stefan D, Anker; George L, Bakri; Gerasimos, Filippato; Christina, Nowack; Peter, Kolkhof; Amer, Joseph; Nicole, Mentenich; Bertram, Pitt; Besada, Diego; Wassermann, Alfredo; Bittar, Julio; Elbert, Alicia; Vallejos, Augusto; Viñes, Gloria; Sanabria, Hugo; Pérez Manghi, Federico; Liberman, Alberto; Bartolacci, Iné; Aizenberg, Diego; Chahin, Mariano; Maffei, Laura; Gelersztein, Elizabeth; Ludvik, Bernhard; Schönherr, Hans-Robert; Drexel, Heinz; Preiß, Wolfgang; Hanusch, Ursula; Neudorfer, Peter; Prischl, Friedrich; Paulweber, Bernhard; Ebenbichler, Christoph; Prager, Rudolf; Sourij, Harald; Schernthaner, Gerit-Holger; Clodi, Martin; Fliesser-Görzer, Evelyn; Ekinci, Elif; Macisaac, Richard; Packham, David; Stephenson, Hugo; Suranyi, Michael; Wittert, Gary; Wynne, Katie-Jane; Pape, Alexia; Topliss, Duncan; Colman, Peter; Nelson, Craig; Vandeleur, Jame; Colquhoun, David; Roger, Simon; Mann Mah, Peak; Abhayaratna, Walter; VAN Gaal, Luc; Gillard, Pieter; Hougardy, Jean-Michel; Speeckaert, Marijn; Stas, Koen; Engelen, Wendy; Duyck, Franci; Scheen, André; Vanbelleghem, Hilde; Doubel, Peter; Vasileva, Svetla; Rashkov, Rosen; Nonchev, Boyan; Temelkova-Kurktschieva, Theodora; Yoncheva-Mihaylova, Mariana; Rangelov, Rangel; Klyuchkova, Neli; Stanchev, Pavel; Tagarev, Zhivko; Boshnyashka, Radostina; Manova, Petya; Prakova, Zhulieta; Lucheva, Mariya; Gushterova, Valentina; Farah, Ghassan; Georgiev, Dimitar; Pichmanova, Mariyana; Minkova, Dotska; Stoyanovska-Elencheva, Bilyana; Eugenia Canziani, Maria; Hissa, Miguel; Noronha, Irene; Eduardo Salles, Joao; Antunes, Daniela; Eliaschewitz, Freddy; Eduardo Figueiredo, Carlo; de Paula, Rogerio; Canani, Lui; Leite Jr, Maurilo; Paolino, Bruno; Rea, Rosangela; Vencio, Sergio; Brito, Claudia; Paschoalin, Raphael; Pecoits Filho, Roberto; Vasconcellos, Eduardo
Publication Year:	2019
Collection:	Università degli Studi di Verona: Catalogo dei Prodotti della Ricerca (IRIS)
Subject Terms:	Aldosterone; Diabetes; Kidney; Mineralocorticoid; Cardiovascular Diseases; Diabetes Mellitus; Type 2; Diabetic Nephropathies; Double-Blind Method; Glomerular Filtration Rate; Mineralocorticoid Receptor Antagonists; Naphthyridines; Renal Insufficiency; Chronic
Description:	Background: Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials. Patients and Methods: The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate >= 25 mL/min/1.73 m(2) and albuminuria (urinary albumin-to-creatinine ratio >= 30 to
Document Type:	article in journal/newspaper
Language:	English
Relation:	info:eu-repo/semantics/altIdentifier/pmid/31665733; info:eu-repo/semantics/altIdentifier/wos/WOS:000498619000003; volume:50; issue:5; firstpage:345; lastpage:356; numberofpages:12; journal:AMERICAN JOURNAL OF NEPHROLOGY; https://hdl.handle.net/11562/1030477
DOI:	10.1159/000503712
Availability:	https://hdl.handle.net/11562/1030477; https://doi.org/10.1159/000503712
Accession Number:	edsbas.A5BB83E8
Database:	BASE