Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
| Title: | Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023 |
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| Authors: | SI Hay; KL Ong; DF Santomauro; A Bhoomadevi; MA Aalipour; H Aalruz; HS Ababneh; UO Abaraogu; BB Abate; C Abbafati; N Abbas; M Abbasifard; M Abbasi-Kangevari; S Abd ElHafeez; AN Abdalla; MA Abdalla; EM Abdallah; BA Abdeeq; NMI Abdel Razeq; AA Abdelgalil; R Abdel-Hameed; M Abdelmasseh; M Abdelnabi; WM Abdel-Rahman; S Abd-Elsalam; S Abdi; M Abdollahi; M Abdoun; A Abdous; JM Abdul Aziz; DM Abdulah; RS Abdulkader; A Abdullahi; T Abdul-Rahman; K Abdykerimova; H Abebe Getahun; A Abedi; AA Abejew; RA Abeldaño Zuñiga; ES Abhilash; SUA Abid; SH Abidi; A Abie; OO Abiodun; O Abiodun; RG Aboagye; S Abohashem; H Abolhassani; US Abonie; NM Abourashed; M Abouzid; D Abramov; LG Abreu; D Abtahi; RK Abu Farha; FHA Abuadas; AK Abubakar; B Abubakar; E Abu-Gharbieh; S Abuhammad; AY Abuhelwa; HJ Abukhadijah; NME Abu-Rmeileh; S Aburuz; D Abushanab; RR Achar; AB Acharya; A Acharya; IN Ackerman; JM Acuna; O Adal; LC Adams; LH Adamu; MM Adane; ZD Addisu; IY Addo; OA Adeagbo; TA Adebisi; IA Adedeji; D Adedia; KA Adedokun; RA Adedoyin; OE Adegbile; OA Adegboye; NA Adegoke; OT Adeleke; IA Adesina; MA Adesina; HO Adewuyi; TE Adeyeoluwa; OI Adeyomoye; K Adhikari; RK Adhikary; U Adiga; M Adnan; QES Adnani; PO Adoma; LA Adzigbli |
| Publication Year: | 2025 |
| Collection: | University of Sussex (US): Figshare |
| Subject Terms: | Biomedical and clinical sciences; Health sciences; Public health; Humans; Global Burden of Disease; Life Expectancy; Risk Factors; Male; Female; Disability-Adjusted Life Years; Wounds and Injuries; Middle Aged; Adult; Global Health; Child; Aged; Adolescent; Infant; Preschool; Young Adult; Newborn; COVID-19; Persons with Disabilities; Quality-Adjusted Life Years; 80 and over; GBD 2023 Disease and Injury and Risk Factor Collaborators; 4206 Public Health; 42 Health Sciences; Coronaviruses; Infectious Diseases |
| Description: | Background For more than three decades, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) has provided a framework to quantify health loss due to diseases, injuries, and associated risk factors. This paper presents GBD 2023 findings on disease and injury burden and risk-attributable health loss, offering a global audit of the state of world health to inform public health priorities. This work captures the evolving landscape of health metrics across age groups, sexes, and locations, while reflecting on the remaining post-COVID-19 challenges to achieving our collective global health ambitions. Methods The GBD 2023 combined analysis estimated years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs) for 375 diseases and injuries, and risk-attributable burden associated with 88 modifiable risk factors. Of the more than 310 000 total data sources used for all GBD 2023 (about 30% of which were new to this estimation round), more than 120 000 sources were used for estimation of disease and injury burden and 59 000 for risk factor estimation, and included vital registration systems, surveys, disease registries, and published scientific literature. Data were analysed using previously established modelling approaches, such as disease modelling meta-regression version 2.1 (DisMod-MR 2.1) and comparative risk assessment methods. Diseases and injuries were categorised into four levels on the basis of the established GBD cause hierarchy, as were risk factors using the GBD risk hierarchy. Estimates stratified by age, sex, location, and year from 1990 to 2023 were focused on disease-specific time trends over the 2010–23 period and presented as counts (to three significant figures) and age-standardised rates per 100 000 person-years (to one decimal place). For each measure, 95% uncertainty intervals [UIs] were calculated with the 2·5th and 97·5th percentile ordered values from a 250-draw distribution. Findings Total numbers of global DALYs grew 6·1% (95% UI ... |
| Document Type: | article in journal/newspaper |
| Language: | unknown |
| Relation: | 10779/uos.31389160.v1 |
| Availability: | https://figshare.com/articles/journal_contribution/Burden_of_375_diseases_and_injuries_risk-attributable_burden_of_88_risk_factors_and_healthy_life_expectancy_in_204_countries_and_territories_including_660_subnational_locations_1990_2023_a_systematic_analysis_for_the_Global_Burden_of_Diseas/31389160 |
| Rights: | CC BY 4.0 |
| Accession Number: | edsbas.A5C4EAE2 |
| Database: | BASE |