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Changes in Arterial-Alveoli Oxygen Gradient During and after Cardiac Surgery in Patients with Congenital Heart Disease

Title: Changes in Arterial-Alveoli Oxygen Gradient During and after Cardiac Surgery in Patients with Congenital Heart Disease
Authors: Ghasemzade, Bahram; Azemati, Simin; Jannati, Mansour; Asgari, Reza
Source: Medical Journal of Dr. D.Y. Patil Vidyapeeth ; volume 16, issue 6, page 934-940 ; ISSN 2589-8302 2589-8310
Publisher Information: Medknow
Publication Year: 2023
Description: A BSTRACT Objective: Disturbance in gas exchange leads to increased ventilation needs, time to stay in the ICU and death. Arterial-alveoli oxygen gradient (A-a) has been studied in adults but has not been considered in children under one year of age who have congenital heart disease and had undergone heart surgery. We decided to examine (A-a) in these patients. Materials and Methods: This study is a retrospective study. Patients were divided into two groups based on mortality. Arterial blood gas information was extracted the post-anesthesia, post-bypass, and 4 hours to 16 hours after surgery. The values (A-a) were calculated using a standard formula. Data were analyzed by SPSS software. P < 0.05 was considered statistically significant. Results: 14 boys and 9 girls were examined. Among these patients, four girls and three boys died. Arterial-alveolar oxygen gradient changes are similar in the living and the dead ( P = 0.508). The mean arterial-alveolar oxygen gradients did not show a significant difference between the alive persons and the dead ( P = 0.337). Arterial-alveolar oxygen gradient changes during the time, and this change was statistically significant ( P = 0.000). Arterial-alveolar oxygen gradient in cardiac surgery in children under one year of age declines up to 16 hours after surgery. The duration of hospitalization ( P = 0.290 (or intubation in the ICU ( P = 0.792) does not affect the alveolar-arterial oxygen gradient. Conclusion: Arterial-alveolar changes in oxygen in heart surgery in children under one year of age were significant during the time and generally decreased 16 hours after the surgery. There was no statistically significant relationship between the length of hospital stay or intubation in the ICU with the arterial alveolar oxygen gradient.
Document Type: article in journal/newspaper
Language: English
DOI: 10.4103/mjdrdypu.mjdrdypu_334_22
Availability: https://doi.org/10.4103/mjdrdypu.mjdrdypu_334_22; https://journals.lww.com/10.4103/mjdrdypu.mjdrdypu_334_22
Accession Number: edsbas.A5DE1957
Database: BASE