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Impact on life expectancy of HIV-1 positive individuals of CD4R cell count and viral load response to antiretroviral therapy

Title: Impact on life expectancy of HIV-1 positive individuals of CD4R cell count and viral load response to antiretroviral therapy
Authors: May, Margaret T.; Gompels, Mark; Delpech, Valerie; Porter, Kholoud; Orkin, Chloe; Kegg, Stephen; Hay, Phillip; Johnson, Margaret; Palfreeman, Adrian; Gilson, Richard; Chadwick, David; Martin, Fabiola; Hill, Teresa; Walsh, John; Post, Frank; Fisher, Martin; Ainsworth, Jonathan; Jose, Sophie; Leen, Clifford; Nelson, Mark; Anderson, Jane; Sabin, Caroline; Babiker, Abdel; Dunn, Daviad; Gazzard, Brian; Phillips, Andrew; Pillay, Deenan; Sachikonye, Memory; Schwenk, Achim; Winston, Alan; Mackie, Nicky
Publisher Information: Lippincott Williams and Wilkins
Publication Year: 2014
Collection: The University of Queensland: UQ eSpace
Subject Terms: Antiretroviral therapy; Cd4 + cell count; HIV; HIV-1 RNA; Life expectancy; Viral load; 2403 Immunology; 2723 Immunology and Allergy; 2725 Infectious Diseases
Description: Objective: The objective of this study is to estimate life expectancies of HIV-positive patients conditional on response to antiretroviral therapy (ART). Methods: Patients aged more than 20 years who started ART during 2000-2010 (excluding IDU) in HIV clinics contributing to the UK CHIC Study were followed for mortality until 2012.Wedetermined the latestCD4+ cell count and viral load before ART and in each of years 1-5 of ART. For each duration of ART, life tables based on estimated mortality rates by sex, age, latest CD4+ cell count and viral suppression (HIV-1 RNA
Document Type: article in journal/newspaper
Language: English
ISSN: 1473-5571; 0269-9370
Relation: orcid:0000-0003-4487-8803; G0000199; G0600337; G0900274; G0700820; MR/J002380/1; MC_UU_12023/15
Availability: https://espace.library.uq.edu.au/view/UQ:96326b5
Accession Number: edsbas.A6969F70
Database: BASE