| Title: |
Regulatory and clinical implications of using diagnostic CT in PET/CT |
| Authors: |
Spadafora, Marco; De Rimini, Maria Luisa; Catalano, Mara; Lastoria, Secondo; Squame, Fiorenzo; Falzarano, Maria; Daniele, Bruno; Cuocolo, Alberto |
| Contributors: |
Spadafora, Marco; De Rimini, Maria Luisa; Catalano, Mara; Lastoria, Secondo; Squame, Fiorenzo; Falzarano, Maria; Daniele, Bruno; Cuocolo, Alberto |
| Publication Year: |
2025 |
| Collection: |
IRIS Università degli Studi di Napoli Federico II |
| Description: |
The introduction of combined positron emission tomography (PET) and computed tomography (CT) scanner has made it possible to acquire, in a single study, complementary morpho-structural and functional/metabolic information. In its standard applications hybrid PET/CT imaging, with a low-dose (LD) CT scan without contrast medium administration, can allow attenuation correction and anatomical cross-sectional of functional PET images, while avoiding the increased radiation burden which, instead, is associated with a full-dose (FD) CT. Nevertheless, the association of PET imaging with FDCT and with contrast-enhanced (CE) CT, i.e. diagnostic CT, has been investigated to increase the diagnostic accuracy of PET/CT in some specific clinical scenarios. There are potential clinical and procedural benefits to using single step combined dual imaging PET and FD-CECT. However, radiation protection regulations, guidelines from scientific societies, local provisions, correct clinical decision making and practical considerations, limit the use of PET/CECT to selected patients in which a clinical or procedural justification must be demonstrated, despite current scientific context where there is a lack of significant studies that support its appropriateness. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/wos/WOS:001478385600001; volume:13; firstpage:275; lastpage:281; numberofpages:7; journal:CLINICAL AND TRANSLATIONAL IMAGING; https://hdl.handle.net/11588/1000876 |
| DOI: |
10.1007/s40336-025-00700-4 |
| Availability: |
https://hdl.handle.net/11588/1000876; https://doi.org/10.1007/s40336-025-00700-4 |
| Rights: |
info:eu-repo/semantics/openAccess ; license:Creative commons ; license uri:http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Accession Number: |
edsbas.A9AADF5 |
| Database: |
BASE |