| Title: |
Age disparities in survival from lymphoma and myeloma: a comparison between US and England |
| Authors: |
Pulte, Dianne; Redaniel, Maria T.; Lowry, Lisa; Bird, Jenny; Jeffreys, Mona |
| Source: |
British Journal of Haematology ; volume 165, issue 6, page 824-831 ; ISSN 0007-1048 1365-2141 |
| Publisher Information: |
Wiley |
| Publication Year: |
2014 |
| Collection: |
Wiley Online Library (Open Access Articles via Crossref) |
| Description: |
Summary Population‐level survival in older patients with lymphoma is significantly lower than in younger patients. In this study, data were obtained from cancer registries in E ngland and the U nited S tates ( US ) for patients diagnosed with H odgkin lymphoma ( HL ), non‐ H odgkin lymphoma ( NHL ) and myeloma. Five‐year relative survival was calculated using period analysis. Generalised linear models were used to determine excess hazard ratios ( EHR ) for older compared to younger patients. Five‐year relative survival was lower for older patients diagnosed with HL , NHL and myeloma in both countries. The greatest age‐related survival inequality was observed for patients with HL : in 2006–10 the EHR comparing patients aged 75 + years with those aged 15–24 years was 14·02 in the US and 15·69 in E ngland. For NHL , the EHR was 1·91 in the US and 3·81 in E ngland. For myeloma, comparing patients aged 75 + years with those aged 25–44 years, the EHR was 2·79 in the US and 3·60 in E ngland. Survival of patients with lymphoma is lower for older patients in both the US and E ngland but the discrepancy is less in the US . Physicians should be encouraged to evaluate patients' frailty and co‐morbidities as well as their age when considering treatment options for patients with lymphoma and myeloma. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1111/bjh.12837 |
| Availability: |
http://dx.doi.org/10.1111/bjh.12837; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fbjh.12837; https://onlinelibrary.wiley.com/doi/pdf/10.1111/bjh.12837 |
| Rights: |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
| Accession Number: |
edsbas.AA1AF8F0 |
| Database: |
BASE |