A DNA prime-live vaccine boost strategy in mice can augment IFN-γ responses to mycobacterial antigens but does not increase the protective efficacy of two attenuated strains of Mycobacterium bovis against bovine tuberculosis
| Title: | A DNA prime-live vaccine boost strategy in mice can augment IFN-γ responses to mycobacterial antigens but does not increase the protective efficacy of two attenuated strains of Mycobacterium bovis against bovine tuberculosis |
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| Authors: | Skinner, Margot A; Ramsey, A J; Buchan, C S; Keen, D L; Slobbe, L; Collins, D M; de Lisle, GW; Buddle, B M; Ranasinghe, Charani |
| Source: | Immunology |
| Publisher Information: | Blackwell Publishing Ltd |
| Publication Year: | 2015 |
| Collection: | Australian National University: ANU Digital Collections |
| Subject Terms: | Keywords: BCG vaccine; DNA vaccine; gamma interferon; immunoglobulin G1; live vaccine; Mycobacterium antigen; plasmid DNA; animal cell; animal model; antibody response; antigen expression; article; attenuation; bacterial strain; cattle disease; controlled study; cy |
| Description: | The Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccine has variable efficacy for both human and bovine tuberculosis. There is a need for improved vaccines or vaccine strategies for control of these diseases. A recently developed prime-boost strate |
| Document Type: | article in journal/newspaper |
| File Description: | application/pdf |
| Language: | unknown |
| Relation: | https://hdl.handle.net/1885/22124 |
| DOI: | 10.1046/j.1365-2567.2003.01589.x |
| Availability: | https://hdl.handle.net/1885/22124; https://doi.org/10.1046/j.1365-2567.2003.01589.x; https://openresearch-repository.anu.edu.au/bitstreams/d967dc78-e161-4294-b55f-b4a8fc01740b/download; https://openresearch-repository.anu.edu.au/bitstreams/ec1727c7-7b70-4208-9110-64f45af10270/download; https://openresearch-repository.anu.edu.au/bitstreams/23b1a8c6-e24a-4732-9409-2ee31280be7f/download |
| Accession Number: | edsbas.AB15EBFC |
| Database: | BASE |