| Title: |
Clinical decision aids and computed tomography coronary angiography in patients with suspected acute coronary syndrome |
| Authors: |
Wang, K.-L.; Taggart, C.; McDermott, M.; O'Brien, R.; Oatey, K.; Keating, L.; Storey, R.F.; Felmeden, D.; Curzen, N.; Kardos, A.; Roobottom, C.; Smith, J.; Goodacre, S.; Newby, D.E.; Gray, A.J. |
| Publisher Information: |
BMJ |
| Publication Year: |
2024 |
| Collection: |
White Rose Research Online (Universities of Leeds, Sheffield & York) |
| Description: |
Background The HEART score, the T-MACS model and the GRACE score support early decision-making for acute chest pain, which could be complemented by CT coronary angiography (CTCA). However, their performance has not been directly compared. Methods In this secondary analysis of a multicentre randomised controlled trial of early CTCA in intermediate-risk patients with suspected acute coronary syndrome, C-statistics and performance metrics (using the predefined cut-offs) of clinical decision aids and CTCA, alone and then in combination, for the index hospital diagnosis of acute coronary syndrome and for 30-day coronary revascularisation were assessed in those who underwent CTCA and had complete data. Results Among 699 patients, 358 (51%) had an index hospital diagnosis of acute coronary syndrome, for which the C-statistic was higher for CTCA (0.80), followed by the T-MACS model (0.78), the HEART score (0.74) and the GRACE score (0.60). The negative predictive value was higher for the absence of coronary artery disease on CTCA (0.90) or a T-MACS estimate of |
| Document Type: |
article in journal/newspaper |
| File Description: |
text |
| Language: |
English |
| ISSN: |
1472-0205 |
| Relation: |
https://eprints.whiterose.ac.uk/id/eprint/214262/1/emermed-2024-213904.pdf; Wang, K.-L. orcid.org/0000-0001-8563-9089 , Taggart, C., McDermott, M. et al. (12 more authors) (2024) Clinical decision aids and computed tomography coronary angiography in patients with suspected acute coronary syndrome. Emergency Medicine Journal, 41 (8). pp. 488-494. ISSN: 1472-0205 |
| Availability: |
https://eprints.whiterose.ac.uk/id/eprint/214262/ |
| Rights: |
cc_by_4 |
| Accession Number: |
edsbas.AB244C61 |
| Database: |
BASE |