| Title: |
Postpandemic Sentinel Surveillance of Respiratory Diseases in the Context of the World Health Organization Mosaic Framework: Protocol for a Development and Evaluation Study Involving the English Primary Care Network 2023-2024 |
| Authors: |
Xinchun Gu; Conall Watson; Utkarsh Agrawal; Heather Whitaker; William H. Elson; Sneha Anand; Ray Borrow; Anna Buckingham; Elizabeth Button; Lottie Curtis; Dominic Dunn; Alex J. Elliot; Filipa Ferreira; Rosalind Goudie; Uy Hoang; Katja Hoschler; Gavin Jamie; Debasish Kar; Beatrix Kele; Meredith Leston; Ezra Linley; Jack Macartney; Gemma L Marsden; Cecilia Okusi; Omid Parvizi; Catherine Quinot; Praveen Sebastianpillai; Vanashree Sexton; Gillian Smith; Timea Suli; Nicholas P B Thomas; Catherine Thompson; Daniel Todkill; Rashmi Wimalaratna; Matthew Inada-Kim; Nick Andrews; Victoria Tzortziou-Brown; Rachel Byford; Maria Zambon; Jamie Lopez-Bernal; Simon de Lusignan |
| Source: |
JMIR Public Health and Surveillance, Vol 10, p e52047 (2024) |
| Publisher Information: |
JMIR Publications |
| Publication Year: |
2024 |
| Collection: |
Directory of Open Access Journals: DOAJ Articles |
| Subject Terms: |
Public aspects of medicine; RA1-1270 |
| Description: |
BackgroundPrepandemic sentinel surveillance focused on improved management of winter pressures, with influenza-like illness (ILI) being the key clinical indicator. The World Health Organization (WHO) global standards for influenza surveillance include monitoring acute respiratory infection (ARI) and ILI. The WHO’s mosaic framework recommends that the surveillance strategies of countries include the virological monitoring of respiratory viruses with pandemic potential such as influenza. The Oxford-Royal College of General Practitioner Research and Surveillance Centre (RSC) in collaboration with the UK Health Security Agency (UKHSA) has provided sentinel surveillance since 1967, including virology since 1993. ObjectiveWe aim to describe the RSC’s plans for sentinel surveillance in the 2023-2024 season and evaluate these plans against the WHO mosaic framework. MethodsOur approach, which includes patient and public involvement, contributes to surveillance objectives across all 3 domains of the mosaic framework. We will generate an ARI phenotype to enable reporting of this indicator in addition to ILI. These data will support UKHSA’s sentinel surveillance, including vaccine effectiveness and burden of disease studies. The panel of virology tests analyzed in UKHSA’s reference laboratory will remain unchanged, with additional plans for point-of-care testing, pneumococcus testing, and asymptomatic screening. Our sampling framework for serological surveillance will provide greater representativeness and more samples from younger people. We will create a biomedical resource that enables linkage between clinical data held in the RSC and virology data, including sequencing data, held by the UKHSA. We describe the governance framework for the RSC. ResultsWe are co-designing our communication about data sharing and sampling, contextualized by the mosaic framework, with national and general practice patient and public involvement groups. We present our ARI digital phenotype and the key data RSC network members are requested to ... |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
https://publichealth.jmir.org/2024/1/e52047; https://doaj.org/toc/2369-2960; https://doaj.org/article/5c9c5cfa45c34dad908cf445ee1582a6 |
| DOI: |
10.2196/52047 |
| Availability: |
https://doi.org/10.2196/52047; https://doaj.org/article/5c9c5cfa45c34dad908cf445ee1582a6 |
| Accession Number: |
edsbas.AB317EC0 |
| Database: |
BASE |