| Title: |
Training, guideline access and knowledge of antiretroviral interactions: Is the South African private sector being left behind? |
| Authors: |
Chisholm, BS; Swart, AM; Blockman, M |
| Source: |
South African Medical Journal ; page 806-811 ; ISSN 2078-5135 0256-9574 |
| Publisher Information: |
South African Medical Association NPC |
| Publication Year: |
2022 |
| Description: |
Background. South Africa (SA) has the largest antiretroviral therapy programme in the world. While the majority of the country accesses healthcare in the public sector, 15.2% access private healthcare. In 2019, dolutegravir was introduced as first-line treatment for HIV. Dolutegravir has clinically significant interactions with numerous commonly used medicines, e.g. rifampicin and cation-containing medicines such as calcium and iron. They require dosage adjustments, detailed in public and private HIV guidelines.Objectives. To describe SA healthcare workers’ guideline access, training and knowledge of dolutegravir’s interactions, focusing ondifferences between the public and private sectors.Methods. A cross-sectional, descriptive study was done using an online survey of healthcare workers in the field of HIV in SA, conducted by the National HIV and TB Healthcare Worker Hotline. Convenience sampling was used, with electronic dissemination to users of the hotline and by relevant HIV-focused organisations. Simple descriptive statistics and statistical analyses were used.Results. A total of 1 939 surveys were analysed, with 22% from the private sector. Training on the dolutegravir guidelines was receivedby significantly fewer healthcare workers in the private sector v. the public sector: 42.4% (95% confidence interval (CI) 37 - 48) v. 67.5%(95% CI I 65 - 70), respectively. Significantly fewer healthcare workers in the private sector had access to the guidelines (63.8%; 95% CI59 - 69 v. 78.8%; 95% CI 77 - 81). When asked if they were aware that dolutegravir has interactions, just over half (56.9%) of healthcareworkers in the private sector responded ‘yes’, 24.6% responded ‘no’ and 18.5% did not answer. Of those who were aware that dolutegravir has interactions, 48.9% knew that dolutegravir interacts with calcium, 44.6% with iron and 82.0% with rifampicin. Private sector knowledge of dosing changes was lower for all interacting drugs, with the difference only significant for calcium and iron. Private sector healthcare ... |
| Document Type: |
article in journal/newspaper |
| Language: |
unknown |
| DOI: |
10.7196/samj.2022.v112i10.16427 |
| Availability: |
https://doi.org/10.7196/samj.2022.v112i10.16427; https://samajournals.co.za/index.php/samj/article/download/263/182 |
| Rights: |
https://creativecommons.org/licenses/by-nc/4.0 |
| Accession Number: |
edsbas.AB7BA8F5 |
| Database: |
BASE |