| Title: |
Prevalence of hepatitis d virus infection in central Italy has remained stable across the last 2 decades with dominance of subgenotypes 1 and characterized by elevated viral replication |
| Authors: |
Salpini, Romina; Piermatteo, Lorenzo; Torre, Giulia; D'Anna, Stefano; Khan, Sohaib; Duca, Leonardo; Bertoli, Ada; La Frazia, Simone; Malagnino, Vincenzo; Teti, Elisabetta; Iannetta, Marco; Paba, Pierpaolo; Ciotti, Marco; Lenci, Ilaria; Francioso, Simona; Paquazzi, Caterina; Lichtner, Miriam; Mastroianni, Claudio; Santopaolo, Francesco; De Sanctis, Giuseppe; Pellicelli, Adriano; Galati, Giovanni; Moretti, Alessandra; Casinelli, Katia; Caterini, Luciano; Iapadre, Nerio; Parruti, Giustino; Vecchiet, Iacopo; Paoloni, Maurizio; Marignani, Massimo; Ceccherini-Silberstein, Francesca; Baiocchi, Leonardo; Grelli, Sandro; Sarmati, Loredana; Svicher, Valentina |
| Contributors: |
Salpini, Romina; Piermatteo, Lorenzo; Torre, Giulia; D'Anna, Stefano; Khan, Sohaib; Duca, Leonardo; Bertoli, Ada; La Frazia, Simone; Malagnino, Vincenzo; Teti, Elisabetta; Iannetta, Marco; Paba, Pierpaolo; Ciotti, Marco; Lenci, Ilaria; Francioso, Simona; Paquazzi, Caterina; Lichtner, Miriam; Mastroianni, Claudio; Santopaolo, Francesco; De Sanctis, Giuseppe; Pellicelli, Adriano; Galati, Giovanni; Moretti, Alessandra; Casinelli, Katia; Caterini, Luciano; Iapadre, Nerio; Parruti, Giustino; Vecchiet, Iacopo; Paoloni, Maurizio; Marignani, Massimo; Ceccherini-Silberstein, Francesca; Baiocchi, Leonardo; Grelli, Sandro; Sarmati, Loredana; Svicher, Valentina |
| Publication Year: |
2024 |
| Collection: |
Sapienza Università di Roma: CINECA IRIS |
| Subject Terms: |
hdv chronic infection; hdv prevalence; hdv-rna quantification; hepatitis b viru; hepatitis d virus |
| Description: |
Objectives: Here we investigate Hepatitis D virus (HDV)-prevalence in Italy and its fluctuations over time and we provide an extensive characterization of HDV-infected patients. Methods: The rate of HDV seroprevalence and HDV chronicity was assessed in 1579 hepatitis B surface antigen (HBsAg)+ patients collected from 2005 to 2022 in Central Italy. Results: In total, 45.3% of HBsAg+ patients received HDV screening with an increasing temporal trend: 15.6% (2005-2010), 45.0% (2011-2014), 49.4% (2015-2018), 71.8% (2019-2022). By multivariable model, factors correlated with the lack of HDV screening were alanine-aminotransferase (ALT) less than two times of upper limit of normality ( |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/37944585; info:eu-repo/semantics/altIdentifier/wos/WOS:001130407500001; volume:138; firstpage:1; lastpage:9; numberofpages:9; journal:INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES; https://hdl.handle.net/11573/1697886 |
| DOI: |
10.1016/j.ijid.2023.11.005 |
| Availability: |
https://hdl.handle.net/11573/1697886; https://doi.org/10.1016/j.ijid.2023.11.005 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.ABBB0470 |
| Database: |
BASE |