| Title: |
Liver Function Test (SGPT) Abnormality in 319 Confirmed COVID-19 Cases in Bangladesh |
| Authors: |
Yesmin, Mahbuba; Biswas, Nirmol Kumar; Alam, Afroja |
| Source: |
Bangladesh Journal of Medicine; Vol. 34 No. 2 (Supplement' May 2023) ; 217 ; 2408-8366 ; 1023-1986 |
| Publisher Information: |
Association of Physicians of Bangladesh |
| Publication Year: |
2023 |
| Collection: |
Bangladesh Journals Online (BanglaJOL) |
| Subject Terms: |
Liver Function Test; SGPT; COVID-19 cases |
| Time: |
Bangladesh |
| Description: |
Background: Deranged liver function abnormalities are well-recognized sequela of COVID-19 infection. Globally, there are studies dedicated to evaluate spectrum of liver injury by COVID-19. In this study, we have described the impact of COVID-19 on liver function tests in 319 confirmed COVID cases. Our study aimed to evaluate the liver function alteration by COVID-19 in our population. Methods: This study included all adult inpatients (> 18 years old) with laboratory confirmed (RT-PCR) COVID-19 from March to April, 2020 in a tertiary COVID dedicated hospital. We assessed liver function test and categorized patients according to COVID severity. This was a single center, retrospective, observational study. Results: Among 319 patients with COVID-19, 36% had normal and 64% had abnormal liver function test. Out of this, 18% had 1-2 times, 42% had 2-3 times and 19% had >3 times upper limit of normal SGPT during admission. 57 (18%) patients presented with mild illness, 83 (26%) with moderate, 124 (39%) patients with severe and 54 (17%) with critical COVID-19 during admission. Significant correlation was found between severity of COVID-19 and raised SGPT level. Conclusion: More than half of patients presented during admission with abnormal liver function. COVID-19 has significant impact on liver function derangement in this population. Bangladesh J Medicine 2023; Vol. 34, No. 2(1) Supplement: 217 |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
https://banglajol.info/index.php/BJMED/article/view/66174/44607; https://banglajol.info/index.php/BJMED/article/view/66174 |
| Availability: |
https://banglajol.info/index.php/BJMED/article/view/66174 |
| Accession Number: |
edsbas.ABD59D71 |
| Database: |
BASE |