Still’s disease continuum from childhood to elderly: data from the international AIDA Network Still’s disease registry
| Title: | Still’s disease continuum from childhood to elderly: data from the international AIDA Network Still’s disease registry |
|---|---|
| Authors: | Vitale A.; Caggiano V.; Lopalco G.; Mayrink Giardini H. A.; Ciccia F.; Almaghlouth I. A.; Ruscitti P.; Sfikakis P. P.; Tufan A.; Dagna L.; Giacomelli R.; Hinojosa-Azaola A.; Ragab G.; Direskeneli H.; Fotis L.; Sota J.; Iannone F.; Morrone M.; de Brito Antonelli I. P.; Dagostin M. A.; Iacono D.; Patrone M.; Asfina K.; Alanazi F.; Cola I. D.; Gaggiano C.; Tektonidou M. G.; Kardas R. C.; Kucuk H.; Campochiaro C.; Tomelleri A.; Navarini L.; Berardicurti O.; Martin-Nares E.; Torres-Ruiz J.; Mahmoud A. A. -M. A.; Alibaz-Oner F.; Kourtesi K.; Tarsia M.; Sfriso P.; Makowska J.; Govoni M.; Torre F. L.; Maggio M. C.; Monti S.; Giudice E. D.; Emmi G.; Bartoloni E.; Hernandez-Rodriguez J.; Gomez-Caverzaschi V.; Maier A.; Simonini G.; Iagnocco A.; Conti G.; Olivieri A. N.; De Paulis A.; Gullo A. L.; Viapiana O.; Wiesik-Szewczyk E.; Erten S.; Ogunjimi B.; Carubbi F.; Tharwat S.; Laskari K.; Costi S.; Triggianese P.; Karamanakos A.; Conforti A.; Frassi M.; Sebastiani G. D.; Gidaro A.; Mauro A.; Balistreri A.; Fabiani C.; Frediani B.; Cantarini L. |
| Contributors: | Vitale, A.; Caggiano, V.; Lopalco, G.; Mayrink Giardini, H. A.; Ciccia, F.; Almaghlouth, I. A.; Ruscitti, P.; Sfikakis, P. P.; Tufan, A.; Dagna, L.; Giacomelli, R.; Hinojosa-Azaola, A.; Ragab, G.; Direskeneli, H.; Fotis, L.; Sota, J.; Iannone, F.; Morrone, M.; de Brito Antonelli, I. P.; Dagostin, M. A.; Iacono, D.; Patrone, M.; Asfina, K.; Alanazi, F.; Cola, I. D.; Gaggiano, C.; Tektonidou, M. G.; Kardas, R. C.; Kucuk, H.; Campochiaro, C.; Tomelleri, A.; Navarini, L.; Berardicurti, O.; Martin-Nares, E.; Torres-Ruiz, J.; Mahmoud, A. A. -M. A.; Alibaz-Oner, F.; Kourtesi, K.; Tarsia, M.; Sfriso, P.; Makowska, J.; Govoni, M.; Torre, F. L.; Maggio, M. C.; Monti, S.; Giudice, E. D.; Emmi, G.; Bartoloni, E.; Hernandez-Rodriguez, J.; Gomez-Caverzaschi, V.; Maier, A.; Simonini, G.; Iagnocco, A.; Conti, G.; Olivieri, A. N.; De Paulis, A.; Gullo, A. L.; Viapiana, O.; Wiesik-Szewczyk, E.; Erten, S.; Ogunjimi, B.; Carubbi, F.; Tharwat, S.; Laskari, K.; Costi, S.; Triggianese, P.; Karamanakos, A.; Conforti, A.; Frassi, M.; Sebastiani, G. D.; Gidaro, A.; Mauro, A.; Balistreri, A.; Fabiani, C.; Frediani, B.; Cantarini, L. |
| Publication Year: | 2023 |
| Collection: | Università degli Studi di Siena: USiena air |
| Subject Terms: | Child; Epidemiology; Still's Disease; Adult-Onset |
| Description: | Objective Still’s disease is more frequently observed in the paediatric context, but a delayed onset is not exceptional both in the adulthood and in the elderly. However, whether paediatric-onset, adult-onset and elderly-onset Still’s disease represent expressions of the same disease continuum or different clinical entities is still a matter of controversy. The aim of this study is to search for any differences in demographic, clinical features and response to treatment between pediatric-onset, adult-onset and elderly-onset Still’s disease. Methods Subjects included in this study were drawn from the International AutoInflammatory Disease Alliance Network registry for patients with Still’s disease. Results A total of 411 patients suffering from Still’s disease were enrolled; the disease occurred in the childhood in 65 (15.8%) patients, in the adult 314 (76.4%) patients and in the elderly in 32 (7.8%) patients. No statistically significant differences at post-hoc analysis were observed in demographic features of the disease between pediatric-onset, adult-onset and elderly-onset Still’s disease. The salmon-coloured skin rash (p=0.004), arthritis (p=0.009) and abdominal pain (p=0.007) resulted significantly more frequent among paediatric patients than in adult cases, while pleuritis (p=0.015) and arthralgia (p |
| Document Type: | article in journal/newspaper |
| File Description: | ELETTRONICO |
| Language: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/38053457; info:eu-repo/semantics/altIdentifier/wos/WOS:001113057500001; volume:9; issue:4; firstpage:1; lastpage:12; numberofpages:12; journal:RMD OPEN; https://hdl.handle.net/11365/1264401; https://rmdopen.bmj.com/content/9/4/e003578; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693888/ |
| DOI: | 10.1136/rmdopen-2023-003578 |
| Availability: | https://hdl.handle.net/11365/1264401; https://doi.org/10.1136/rmdopen-2023-003578; https://rmdopen.bmj.com/content/9/4/e003578; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693888/ |
| Rights: | info:eu-repo/semantics/openAccess |
| Accession Number: | edsbas.ABFCAAAF |
| Database: | BASE |