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Monocyte and bone marrow macrophage transcriptional phenotypes in systemic juvenile idiopathic arthritis reveal TRIM8 as a mediator of IFN-γ hyper-responsiveness and risk for macrophage activation syndrome

Title: Monocyte and bone marrow macrophage transcriptional phenotypes in systemic juvenile idiopathic arthritis reveal TRIM8 as a mediator of IFN-γ hyper-responsiveness and risk for macrophage activation syndrome
Authors: Schulert, Grant S; Pickering, Alex V; Do, Thuy; Dhakal, Sanjeev; Fall, Ndate; Schnell, Daniel; Medvedovic, Mario; Salomonis, Nathan; Thornton, Sherry; Grom, Alexei A
Contributors: Systemic JIA Foundation; National Institutes of Health; Cincinnati Children's Research Foundation; Jellen Family Foundation
Source: Annals of the Rheumatic Diseases ; volume 80, issue 5, page 617-625 ; ISSN 0003-4967
Publisher Information: Elsevier BV
Publication Year: 2021
Collection: ScienceDirect (Elsevier - Open Access Articles via Crossref)
Document Type: article in journal/newspaper
Language: English
DOI: 10.1136/annrheumdis-2020-217470
Availability: https://doi.org/10.1136/annrheumdis-2020-217470; https://api.elsevier.com/content/article/PII:S0003496724102270?httpAccept=text/xml; https://api.elsevier.com/content/article/PII:S0003496724102270?httpAccept=text/plain; https://syndication.highwire.org/content/doi/10.1136/annrheumdis-2020-217470
Rights: https://www.elsevier.com/tdm/userlicense/1.0/ ; https://www.elsevier.com/legal/tdmrep-license
Accession Number: edsbas.ACAE214
Database: BASE