| Title: |
Increasing importance of anthelmintic resistance in European livestock: creation and meta-analysis of an open database |
| Authors: |
Rose Vineer, Hannah; Morgan, Eric R; Hertzberg, Hubertus; Bartley, David J; Bosco, Antonio; Charlier, Johannes; Chartier, Christophe; Claerebout, Edwin; de Waal, Theo; Hendrickx, Guy; Hinney, Barbara; Höglund, Johan; Ježek, Jožica; Kašný, Martin; Keane, Orla M; Martínez-Valladares, María; Mateus, Teresa Letra; McIntyre, Jennifer; Mickiewicz, Marcin; Munoz, Ana Maria; Phythian, Clare Joan; Ploeger, Harm W; Rataj, Aleksandra Vergles; Skuce, Philip J; Simin, Stanislav; Sotiraki, Smaragda; Spinu, Marina; Stuen, Snorre; Thamsborg, Stig Milan; Vadlejch, Jaroslav |
| Source: |
Rose Vineer, Hannah; Morgan, Eric R; Hertzberg, Hubertus; Bartley, David J; Bosco, Antonio; Charlier, Johannes; Chartier, Christophe; Claerebout, Edwin; de Waal, Theo; Hendrickx, Guy; Hinney, Barbara; Höglund, Johan; Ježek, Jožica; Kašný, Martin; Keane, Orla M; Martínez-Valladares, María; Mateus, Teresa Letra; McIntyre, Jennifer; Mickiewicz, Marcin; Munoz, Ana Maria; Phythian, Clare Joan; Ploeger, Harm W; Rataj, Aleksandra Vergles; Skuce, Philip J; Simin, Stanislav; Sotiraki, Smaragda; Spinu, Marina; Stuen, Snorre; Thamsborg, Stig Milan; Vadlejch, Jaroslav; et al (2020). Increasing importance of anthelmintic resistance in European livestock: creation and meta-analysis of an open database. Parasite, 27:69. |
| Publisher Information: |
Princeps Editions |
| Publication Year: |
2020 |
| Collection: |
University of Zurich (UZH): ZORA (Zurich Open Repository and Archive |
| Subject Terms: |
Institute of Parasitology; 570 Life sciences; biology; 610 Medicine & health; 600 Technology; General Agricultural and Biological Sciences; Parasitology; Anthelmintic resistance; Database; Europe; Gastrointestinal nematodes; Liver fluke; Maps; Prevalence; Ruminants |
| Description: |
Helminth infections are ubiquitous in grazing ruminant production systems, and are responsible for significant costs and production losses. Anthelmintic Resistance (AR) in parasites is now widespread throughout Europe, although there are still gaps in our knowledge in some regions and countries. AR is a major threat to the sustainability of modern ruminant livestock production, resulting in reduced productivity, compromised animal health and welfare, and increased greenhouse gas emissions through increased parasitism and farm inputs. A better understanding of the extent of AR in Europe is needed to develop and advocate more sustainable parasite control approaches. A database of European published and unpublished AR research on gastrointestinal nematodes (GIN) and liver fluke (Fasciola hepatica) was collated by members of the European COST Action "COMBAR" (Combatting Anthelmintic Resistance in Ruminants), and combined with data from a previous systematic review of AR in GIN. A total of 197 publications on AR in GIN were available for analysis, representing 535 studies in 22 countries and spanning the period 1980-2020. Reports of AR were present throughout the European continent and some reports indicated high within-country prevalence. Heuristic sample size-weighted estimates of European AR prevalence over the whole study period, stratified by anthelmintic class, varied between 0 and 48%. Estimated regional (country) prevalence was highly heterogeneous, ranging between 0% and 100% depending on livestock sector and anthelmintic class, and generally increased with increasing research effort in a country. In the few countries with adequate longitudinal data, there was a tendency towards increasing AR over time for all anthelmintic classes in GIN: aggregated results in sheep and goats since 2010 reveal an average prevalence of resistance to benzimidazoles (BZ) of 86%, macrocyclic lactones except moxidectin (ML) 52%, levamisole (LEV) 48%, and moxidectin (MOX) 21%. All major GIN genera survived treatment in various ... |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| ISSN: |
1252-607X |
| Relation: |
https://www.zora.uzh.ch/id/eprint/193329/1/Vincer_et_al.,_Parasite_27_69%282020%29_1388.pdf; urn:issn:1252-607X |
| DOI: |
10.1051/parasite/2020062 |
| Availability: |
https://www.zora.uzh.ch/id/eprint/193329/; https://www.zora.uzh.ch/id/eprint/193329/1/Vincer_et_al.,_Parasite_27_69%282020%29_1388.pdf; https://doi.org/10.1051/parasite/2020062 |
| Rights: |
info:eu-repo/semantics/openAccess ; Creative Commons: Attribution 4.0 International (CC BY 4.0) ; http://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.ACD01DF4 |
| Database: |
BASE |