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Air‐Stable, Phosphine‐Free Anionic Palladacyclopentadienyl Catalysts: Remarkable Halide and Pseudohalide Effects in Stille Coupling

Title: Air‐Stable, Phosphine‐Free Anionic Palladacyclopentadienyl Catalysts: Remarkable Halide and Pseudohalide Effects in Stille Coupling
Authors: Crawforth, Catherine M.; Fairlamb, Ian J. S.; Kapdi, Anant R.; Serrano, José Luis; Taylor, Richard J. K.; Sanchez, Gregorio
Source: Advanced Synthesis & Catalysis ; volume 348, issue 4-5, page 405-412 ; ISSN 1615-4150 1615-4169
Publisher Information: Wiley
Publication Year: 2006
Collection: Wiley Online Library (Open Access Articles via Crossref)
Description: The Stille cross‐coupling of allylic and benzyl bromides is shown to proceed efficiently using phosphine‐free dinuclear anionic palladacyclopentadienyl catalysts possessing bridging ( N , O )‐imidate ligands. The type of bridging anion influences the catalytic activity considerably. Halide anions such as chloride, bromide or iodide also influence the catalytic activity but to a far lesser extent than the pseudohalide imidate anions (from succinimide or phthalimide). A Baldwin‐type cooperative effect is seen with 7a using CuI as a co‐catalyst, in the presence of two equivalents of CsF in DMF at 40 °C. In toluene, these additives slow down substrate turnover.
Document Type: article in journal/newspaper
Language: English
DOI: 10.1002/adsc.200505325
Availability: https://doi.org/10.1002/adsc.200505325; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fadsc.200505325; https://onlinelibrary.wiley.com/doi/pdf/10.1002/adsc.200505325
Rights: http://onlinelibrary.wiley.com/termsAndConditions#vor
Accession Number: edsbas.AD2A1724
Database: BASE