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The case for eliminating excessive worry as a requirement for generalized anxiety disorder:A cross-national investigation

Title: The case for eliminating excessive worry as a requirement for generalized anxiety disorder:A cross-national investigation
Authors: Ruscio, Ayelet Meron; Rassaby, Madeleine; Stein, Murray B.; Stein, Dan J.; Aguilar-Gaxiola, Sergio; Al-Hamzawi, Ali; Alonso, Jordi; Atwoli, Lukoye; Borges, Guilherme; Bromet, Evelyn J.; Bruffaerts, Ronny; Bunting, Brendan; Cardoso, Graça; Chardoul, Stephanie; De Girolamo, Giovanni; De Jonge, Peter; Gureje, Oye; Haro, Josep Maria; Karam, Elie G.; Karam, Aimee; Kiejna, Andrzej; Kovess-Masfety, Viviane; Lee, Sue; Navarro-Mateu, Fernando; Nishi, Daisuke; Piazza, Marina; Posada-Villa, José; Sampson, Nancy A.; Scott, Kate M.; Slade, Tim; Stagnaro, Juan Carlos; Torres, Yolanda; Viana, Maria Carmen; Vladescu, Cristian; Zarkov, Zahari; Kessler, Ronald C.
Source: Ruscio, A M, Rassaby, M, Stein, M B, Stein, D J, Aguilar-Gaxiola, S, Al-Hamzawi, A, Alonso, J, Atwoli, L, Borges, G, Bromet, E J, Bruffaerts, R, Bunting, B, Cardoso, G, Chardoul, S, De Girolamo, G, De Jonge, P, Gureje, O, Haro, J M, Karam, E G, Karam, A, Kiejna, A, Kovess-Masfety, V, Lee, S, Navarro-Mateu, F, Nishi, D, Piazza, M, Posada-Villa, J, Sampson, N A, Scott, K M, Slade, T, Stagnaro, J C, Torres, Y, Viana, M C, Vladescu, C, Zarkov, Z & Kessler, R C 2024, 'The case for eliminating excessive worry as a requirement for generalized anxiety ....
Publication Year: 2024
Collection: University of Groningen research database
Subject Terms: classification; diagnosis; epidemiology; generalized anxiety disorder; global mental health; worry
Description: Background Around the world, people living in objectively difficult circumstances who experience symptoms of generalized anxiety disorder (GAD) do not qualify for a diagnosis because their worry is not 'excessive' relative to the context. We carried out the first large-scale, cross-national study to explore the implications of removing this excessiveness requirement. Methods Data come from the World Health Organization World Mental Health Survey Initiative. A total of 133 614 adults from 12 surveys in Low- or Middle-Income Countries (LMICs) and 16 surveys in High-Income Countries (HICs) were assessed with the Composite International Diagnostic Interview. Non-excessive worriers meeting all other DSM-5 criteria for GAD were compared to respondents meeting all criteria for GAD, and to respondents without GAD, on clinically-relevant correlates. Results Removing the excessiveness requirement increases the global lifetime prevalence of GAD from 2.6% to 4.0%, with larger increases in LMICs than HICs. Non-excessive and excessive GAD cases worry about many of the same things, although non-excessive cases worry more about health/welfare of loved ones, and less about personal or non-specific concerns, than excessive cases. Non-excessive cases closely resemble excessive cases in socio-demographic characteristics, family history of GAD, and risk of temporally secondary comorbidity and suicidality. Although non-excessive cases are less severe on average, they report impairment comparable to excessive cases and often seek treatment for GAD symptoms. Conclusions Individuals with non-excessive worry who meet all other DSM-5 criteria for GAD are clinically significant cases. Eliminating the excessiveness requirement would lead to a more defensible GAD diagnosis.
Document Type: article in journal/newspaper
File Description: application/pdf
Language: English
ISSN: 0033-2917; 1469-8978
Relation: info:eu-repo/semantics/altIdentifier/hdl/https://hdl.handle.net/11370/ce91b17d-a08c-46e8-8ab0-6f6557ea407e; info:eu-repo/semantics/altIdentifier/pissn/0033-2917; info:eu-repo/semantics/altIdentifier/eissn/1469-8978
DOI: 10.1017/S003329172400182X
Availability: https://hdl.handle.net/11370/ce91b17d-a08c-46e8-8ab0-6f6557ea407e; https://research.rug.nl/en/publications/ce91b17d-a08c-46e8-8ab0-6f6557ea407e; https://doi.org/10.1017/S003329172400182X; https://pure.rug.nl/ws/files/1158641310/the-case-for-eliminating-excessive-worry-as-a-requirement-for-generalized-anxiety-disorder-a-cross-national-investigation.pdf; https://www.scopus.com/pages/publications/85207468396
Rights: info:eu-repo/semantics/openAccess ; http://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.AE349783
Database: BASE