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Efficacy of Liquid Embolic Agent Treatment in Hemorrhagic Peripheral Intracranial Aneurysms: A Single-Center Experience

Title: Efficacy of Liquid Embolic Agent Treatment in Hemorrhagic Peripheral Intracranial Aneurysms: A Single-Center Experience
Authors: Zong Zhuang; Qi Zhu; Xun-Zhi Liu; Hai-Ping Ling; Shi-Jie Na; Tao Liu; Yu-Hua Zhang; Chun-Hua Hang; Kai-Dong Liu; Qing-Rong Zhang
Source: Brain Sciences, Vol 12, Iss 1264, p 1264 (2022)
Publisher Information: MDPI AG
Publication Year: 2022
Collection: Directory of Open Access Journals: DOAJ Articles
Subject Terms: peripheral intracranial aneurysm; brain hemorrhage; liquid embolization agents; interventional therapy; Neurosciences. Biological psychiatry. Neuropsychiatry; RC321-571
Description: Objective: To evaluate the efficacy of liquid embolization agents for treating various hemorrhagic peripheral intracranial aneurysms. Methods : We retrospectively analyzed 38 patients who suffered from hemorrhagic peripheral intracranial aneurysms and were treated with liquid embolization agents. We used the modified Rankin scale for follow-up at 6 months postoperatively, and digital subtraction angiography follow-up was performed 6 months postoperatively. Results : Of the 38 patients (ten of simple peripheral intracranial aneurysms, six of Moyamoya disease (MMD), and 22 of arteriovenous malformation (AVM)), posterior circulation accounted for the most significant proportion (57.9%), followed by anterior circulation (21.1%) and intranidal aneurysms (21.1%). Intraoperative hemorrhage occurred in four cases, postoperative cerebral infarction occurred in four cases, two patients encountered microcatheter retention, and intraoperative thrombosis took place in the basilar artery of a patient with an arteriovenous malformation. A postoperative hemorrhage occurred in only one patient. At 6-month follow-up, 84.2% of patients had good prognosis outcomes, and 13.5% had poor outcomes. Conclusion: Liquid embolization agents are effective for hemorrhagic peripheral intracranial aneurysms; however, safety depends on the subtypes. For peripheral hemorrhagic aneurysms in MMD, the vessel architecture must be carefully evaluated before embolization.
Document Type: article in journal/newspaper
Language: English
Relation: https://www.mdpi.com/2076-3425/12/9/1264; https://doaj.org/toc/2076-3425; https://doaj.org/article/0463563f931d4c719d868c2bff74551c
DOI: 10.3390/brainsci12091264
Availability: https://doi.org/10.3390/brainsci12091264; https://doaj.org/article/0463563f931d4c719d868c2bff74551c
Accession Number: edsbas.AE8FF426
Database: BASE