| Title: |
Prior psychiatric hospitalization is associated with excess mortality in patients hospitalized with non-cardiac chest pain: a data linkage study based on the full Scottish population (1991-2006) |
| Authors: |
Gillies, Michelle; Jhund, Pardeep S.; MacTeague, Karen; MacIntyre, Paul; Allardyce, Judith; Batty, G. David; MacIntyre, Kate |
| Publisher Information: |
Oxford University Press |
| Publication Year: |
2012 |
| Collection: |
HighWire Press (Stanford University) |
| Subject Terms: |
Prevention and epidemiology |
| Description: |
Aims Non-cardiac chest pain (NCCP) is considered a benign condition. We investigate case-fatality following an incident hospitalization for NCCP and determine whether previous psychiatric hospitalization is associated with short-term mortality. Methods and results This was a population-based retrospective cohort study of 159 888 patients discharged from hospital in Scotland (1991–2006) following a first NCCP hospitalization, using routinely collected morbidity and mortality data. All-cause and cardiovascular disease (CVD) mortality at 1 year following hospitalization was examined. A total of 3514 (4.4%) men and 3136 (3.9%) women with a first NCCP hospitalization had a psychiatric hospitalization in the 10 years preceding incident NCCP hospitalization. Those with a previous psychiatric hospitalization were younger and more socioeconomically deprived (SED). Overall, crude case fatality at 1 year was 4.4% in men and 3.7% in women. This was higher in patients with a previous psychiatric hospitalization compared with those without (overall: men 6.3 vs. 4.3%; women: 5.3 vs. 3.6%), in all age groups and all SED quintiles. Following adjustment (year of NCCP hospitalization, SED, co-morbid diabetes, and hypertension), the hazard of all-cause and CVD-specific death at 1 year was higher in men and women with a previous psychiatric hospitalization than without, with effect modification according to age group. Conclusion Non-cardiac chest pain is not an entirely benign condition. Individuals with a hospital discharge diagnosis of NCCP who have a previous psychiatric hospitalization have a greater risk of death, all-cause, and CVD-specific, at 1 year, than those without. A NCCP hospitalization is an opportunity to engage, and where appropriate, intervene to modify cardiovascular risk in this difficult-to-reach and high-risk group. |
| Document Type: |
text |
| File Description: |
text/html |
| Language: |
English |
| Relation: |
http://eurheartj.oxfordjournals.org/cgi/content/short/33/6/760; http://dx.doi.org/10.1093/eurheartj/ehr401 |
| DOI: |
10.1093/eurheartj/ehr401 |
| Availability: |
http://eurheartj.oxfordjournals.org/cgi/content/short/33/6/760; https://doi.org/10.1093/eurheartj/ehr401 |
| Rights: |
Copyright (C) 2012, European Society of Cardiology |
| Accession Number: |
edsbas.AEE8F1CD |
| Database: |
BASE |