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In Vitro Development of Resistance to Six Quinolones in Streptococcus pneumoniae, Streptococcus pyogenes , and Staphylococcus aureus

Title: In Vitro Development of Resistance to Six Quinolones in Streptococcus pneumoniae, Streptococcus pyogenes , and Staphylococcus aureus
Authors: Boos, Mechthild; Mayer, Susanne; Fischer, Ansgar; Köhrer, Karl; Scheuring, Sibylle; Heisig, Peter; Verhoef, Jan; Fluit, Ad C.; Schmitz, F.-J.
Source: Antimicrobial Agents and Chemotherapy ; volume 45, issue 3, page 938-942 ; ISSN 0066-4804 1098-6596
Publisher Information: American Society for Microbiology
Publication Year: 2001
Description: Streptococcus pneumoniae, Streptococcus pyogenes , and Staphylococcus aureus isolates were exposed to subinhibitory MICs of ciprofloxacin, sparfloxacin, gatifloxacin, moxifloxacin, clinafloxacin, and gemifloxacin during a 10-day period. Subculturing led to resistance development, regardless of the initial potencies of the quinolones. None of the quinolones was associated with a significantly slower rate of resistance development.
Document Type: article in journal/newspaper
Language: English
DOI: 10.1128/aac.45.3.938-942.2001
DOI: 10.1128/AAC.45.3.938-942.2001
Availability: https://doi.org/10.1128/aac.45.3.938-942.2001; https://journals.asm.org/doi/pdf/10.1128/AAC.45.3.938-942.2001
Rights: https://journals.asm.org/non-commercial-tdm-license
Accession Number: edsbas.AFBAC13D
Database: BASE