| Title: |
APOE ε4 is associated with younger age at ischemic stroke onset but not with stroke outcome |
| Authors: |
Lagging, Cecilia; Lorentzen, Erik; Stanne, Tara M.; Pedersen, Annie; Soderholm, Martin; Cole, John W.; Jood, Katarina; Lemmens, Robin; Phuah, Chia-Ling; Rost, Natalia S.; Thijs, Vincent; Woo, Daniel; Maguire, Jane M.; Lindgren, Arne; Jern, Christina |
| Source: |
ISSN:0028-3878 ; ISSN:1526-632X ; Neurology, vol. 93 (19), (849-853. |
| Publisher Information: |
American Academy of Neurology |
| Publication Year: |
2019 |
| Subject Terms: |
APOLIPOPROTEIN-E GENOTYPE; Clinical Neurology; INTRACEREBRAL HEMORRHAGE; Life Sciences & Biomedicine; Neurosciences & Neurology; POLYMORPHISM; RISK; Science & Technology; Age of Onset; Alleles; Apolipoprotein E2; Apolipoprotein E3; Apolipoprotein E4; Brain Ischemia; Genome-Wide Association Study; Genotype; Humans; Single Nucleotide; Prognosis; Severity of Illness Index; Sex Factors; Stroke; Genetics of Ischaemic Stroke Functional Outcome (GISCOME) network and the International Stroke Genetics Consortium; 1103 Clinical Sciences; 1109 Neurosciences; 1702 Cognitive Sciences; Neurology & Neurosurgery; 3202 Clinical sciences; 3209 Neurosciences |
| Description: |
sponsorship: This study was funded by the Swedish Heart and Lung Foundation (C. Jern and A. Lindgren); the Swedish Research Council (C. Jern); the Swedish Stroke Association (C. Jern and A. Lindgren); the Swedish state under the agreement between the Swedish government and the county councils, the ALF agreement (C. Jern and A. Lindgren); the Gothenburg Foundation for Neurological Research (C. Lagging); the Freemasons Lodge of Instruction EOS in Lund (A. Lindgren); the Foundation of Fars & Frosta-one of Sparbanken Skane's ownership foundations (A. Lindgren); Lund University (A. Lindgren); Region Skane, Skane University Hospital (A. Lindgren); the National Health and Medical Research Council, Australia (J.M. Maguire); the National Institutes of Health (J. Cole); the US Department of Veterans Affairs (J. Cole); the American Heart Association (AHA) Cardiovascular Genome-Phenome Study (J. Cole); and the NIH-NINDS (N.S. Rost). Funding for the entire GISCOME study is listed in Soderholm et al. Genome-wide association meta-analysis of functional outcome after ischemic stroke. (Swedish Heart and Lung Foundation, Swedish Research Council, Swedish Stroke Association, Swedish government, Gothenburg Foundation for Neurological Research, Foundation of Fars AMP; Frosta-one of Sparbanken Skane's ownership foundations, Lund University, Region Skane, Skane University Hospital, ALF agreement, National Health and Medical Research Council, Australia, National Institutes of Health, US Department of Veterans Affairs, American Heart Association (AHA), NIH-NINDS) ; status: Published |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
https://lirias.kuleuven.be/handle/123456789/646304; https://doi.org/10.1212/WNL.0000000000008459; https://pubmed.ncbi.nlm.nih.gov/31619479 |
| DOI: |
10.1212/WNL.0000000000008459 |
| Availability: |
https://lirias.kuleuven.be/handle/123456789/646304; https://lirias.kuleuven.be/retrieve/b461cf62-e1c0-408e-81a7-5d97ae45ed72; https://doi.org/10.1212/WNL.0000000000008459; https://pubmed.ncbi.nlm.nih.gov/31619479 |
| Rights: |
info:eu-repo/semantics/openAccess ; public |
| Accession Number: |
edsbas.B02B2730 |
| Database: |
BASE |