| Title: |
The impact of post-operative enteral nutrition on duodenal injury outcomes: A post hoc analysis of an EAST multicenter trial. |
| Authors: |
Choron, Rachel L; Rallo, Michael; Piplani, Charoo; Youssef, Sara; Teichman, Amanda L; Bargoud, Christopher G; Sciarretta, Jason D; Smith, Randi N; Hanos, Dustin S; Afif, Iman N; Beard, Jessica H; Dhillon, Navpreet K; Zhang, Ashling; Ghneim, Mira; Devasahayam, Rebekah J; Gunter, Oliver L; Smith, Alison A; Sun, Brandi L; Cao, Chloe; Reynolds, Jessica K; Hilt, Lauren A; Holena, Daniel; Chang, Grace; Jonikas, Meghan; Echeverria, Karla; Fung, Nathaniel; Anderson, Aaron; Dumas, Ryan P; Fitzgerald, Caitlin A; Levin, Jeremy; Trankiem, Christine; Yoon, JaeHee Jane; Blank, Jacqueline; Hazelton, Joshua; McLaughlin, Christopher J; Al-Aref, Rami; Kirsch, Jordan M; Howard, Daniel S; Scantling, Dane R; Dellonte, Kate; Vella, Michael; Hopkins, Brent; Shell, Chloe; Udekwu, Pascal O; Wong, Evan G; Joseph, Bellal A; Lieberman, Howard; Ramsey, Walter; Stewart, Collin; Alvarez, Claudia; Berne, John D; Nahmias, Jeffry; Puente, Ivan; Patton, J Pat; Rakitin, Ilya; Perea, Lindsey L; Pulido, Odessa R; Ahmed, Hashim; Keating, Jane; Kodadek, Lisa; Wade, Jason; Henry, Reynold; Schreiber, Martin; Benjamin, Andrew; Khan, Abid; Mann, Laura K; Mentzer, Caleb; Mousafeiris, Vasileios; Mulita, Francesk; Reid-Gruner, Shari; Sais, Erica; Foote, Christopher; Palacio-Lascano, Carlos; Argandykov, Dias; Kaafarani, Haytham; Bover Manderski, Michelle; Narayan, Mayur; Seamon, Mark J |
| Source: |
General Surgery Resident Research |
| Publication Year: |
2024 |
| Collection: |
Philadelphia College of Osteopathic Medicine: DigitalCommons@PCOM |
| Subject Terms: |
Duodenal injury; duodenal leak; enteral nutrition; pancreatic injury; parenteral nutrition; Surgery |
| Description: |
BACKGROUND: Leak following surgical repair of traumatic duodenal injuries results in prolonged hospitalization and oftentimes nil per os(NPO) treatment. Parenteral nutrition(PN) has known morbidity; however, duodenal leak(DL) patients often have complex injuries and hospital courses resulting in barriers to enteral nutrition(EN). We hypothesized EN alone would be associated with 1)shorter duration until leak closure and 2)less infectious complications and shorter hospital length of stay(HLOS) compared to PN. METHODS: This was a post-hoc analysis of a retrospective, multicenter study from 35 Level-1 trauma centers, including patients >14 years-old who underwent surgery for duodenal injuries(1/2010-12/2020) and endured post-operative DL. The study compared nutrition strategies: EN vs PN vs EN + PN using Chi-Square and Kruskal-Wallis tests; if significance was found pairwise comparison or Dunn's test were performed. RESULTS: There were 113 patients with DL: 43 EN, 22 PN, and 48 EN + PN. Patients were young(median age 28 years-old) males(83.2%) with penetrating injuries(81.4%). There was no difference in injury severity or critical illness among the groups, however there were more pancreatic injuries among PN groups. EN patients had less days NPO compared to both PN groups(12 days[IQR23] vs 40[54] vs 33[32],p = |
| Document Type: |
text |
| Language: |
unknown |
| Relation: |
https://digitalcommons.pcom.edu/general_surgery_residents/22 |
| DOI: |
10.1097/TA.0000000000004303 |
| Availability: |
https://digitalcommons.pcom.edu/general_surgery_residents/22; https://doi.org/10.1097/TA.0000000000004303 |
| Accession Number: |
edsbas.B07A9BEB |
| Database: |
BASE |