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Classification and Diagnosis of Trigeminal Autonomic Cephalalgias

Title: Classification and Diagnosis of Trigeminal Autonomic Cephalalgias
Authors: Root, Shane; Knievel, Kerry L.
Contributors: Levin, Morris
Source: Comprehensive Review of Headache Medicine ; page 123-133 ; ISBN 0190888776 9780190888770 9780190888800
Publisher Information: Oxford University PressNew York
Publication Year: 2025
Description: Trigeminal autonomic cephalalgia (TAC) is a group of primary headache disorders characterized by unilateral moderate to severe pain in the periorbital and temporal region with associated ipsilateral cranial autonomic features. It is important to differentiate these headaches from potentially dangerous secondary headache mimics, including headaches with vascular, neoplastic, ocular, and pituitary-related causes. TAC headaches are differentiated by the duration and frequency of attacks, subtle differences in associated features, and response to specific treatments. The pathophysiology of TACs is thought to involve the trigeminovascular afferent system as well as the hypothalamus, which is thought to be the source of the diurnal variation of some of the TAC subtypes as well as the cranial autonomic features.
Document Type: book part
Language: English
ISBN: 978-0-19-088877-0; 978-0-19-088880-0; 0-19-088877-6; 0-19-088880-6
DOI: 10.1093/med/9780190888770.003.0009
Availability: https://doi.org/10.1093/med/9780190888770.003.0009; https://academic.oup.com/book/60688/chapter/526943493
Accession Number: edsbas.B12AA948
Database: BASE