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Median Arcuate Ligament Syndrome: Where Are We Today?

Title: Median Arcuate Ligament Syndrome: Where Are We Today?
Authors: Maddox, Kayden; Farrell, Timothy M.; Pascarella, Luigi
Source: The American Surgeon™, 91(2)
Publisher Information: SAGE Publications
Publication Year: 2025
Collection: Carolina Digital Repository (UNC - University of North Carolina)
Subject Terms: vascular surgery; esophagus/foregut; history; minimally invasive surgery; surgical quality
Description: Median arcuate ligament syndrome, or celiac artery compression syndrome (eponym: Dunbar syndrome), has historically been attributed to pathophysiologic vascular compression causing downstream ischemic symptoms of the organs supplied by the celiac trunk. However, the more we learn about the histology, clinical presentation, and treatment outcomes, health care providers are increasingly correlating the symptoms of MALS with the long-term, repetitive compression of the celiac ganglion rather than the celiac trunk. This article provides a comprehensive review of current MALS literature, emphasizing the multidisciplinary approach these patients require in all phases of their care. With most patients with MALS waiting an average of 10.5 months to 2.6 years, 9, 10 our need for better diagnostic protocols and clearer understanding of the pathophysiology of the disease is paramount. Further investigation into patient outcomes, associated conditions, and linked pathophysiology would help better characterize this disease with hopes of moving it from a diagnosis of exclusion to one of standard work-up with decreased time to treatment and symptom relief for patients.
Document Type: article in journal/newspaper
Language: unknown
Relation: https://cdr.lib.unc.edu/downloads/8s45qq60c?file=thumbnail; https://cdr.lib.unc.edu/downloads/8s45qq60c
DOI: 10.17615/h7sn-vb53
Availability: https://doi.org/10.17615/h7sn-vb53; https://cdr.lib.unc.edu/downloads/8s45qq60c?file=thumbnail; https://cdr.lib.unc.edu/downloads/8s45qq60c
Rights: http://rightsstatements.org/vocab/InC/1.0/ ; http://creativecommons.org/licenses/by-nc/4.0/
Accession Number: edsbas.B17FAB2B
Database: BASE