| Title: |
Impact of Diabetes Mellitus and Its Comorbidities on Elderly Patients Hospitalized in Internal Medicine Wards: Data from the RePoSi Registry |
| Authors: |
Argano C; Natoli G; Mularo S; Nobili A; Lo Monaco M; Mannucci PM; Perticone F; Pietrangelo A; Corrao S; REPOSI Investigators; Mecocci P; Ruggiero C; Boccardi V |
| Contributors: |
Argano, C; Natoli, G; Mularo, S; Nobili, A; Lo Monaco, M; Mannucci, Pm; Perticone, F; Pietrangelo, A; Corrao, S; Reposi, Investigator; Mecocci, P; Ruggiero, C; Boccardi, V |
| Publication Year: |
2022 |
| Collection: |
IRIS Università degli Studi di Perugia |
| Subject Terms: |
1-year mortality; Cancer; Comorbidities; Diabetes; Heart rate; In-hospital mortality; Male sex |
| Description: |
Background: Currently, diabetes represents the seventh leading cause of death worldwide, with a significant economic burden. The number and severity of comorbidities increase with age, and are identified as important determinants that influence the prognosis. We aimed to investigate comorbidities and outcomes in a cohort of hospitalized elderly patients affected by diabetes. Methods: In this observational study, we retrospectively analyzed data collected from the REgistro dei pazienti per lo studio delle POlipatologie e politerapie in reparti della rete Simi (RePoSi) reg-istry. Socio-demographic, clinical characteristics, and laboratory findings were considered. The association between variables and in-hospital and 1-year follow-up were analyzed. Results: Among 4708 in-patients, 1378 (29.3%) had a diagnosis of diabetes. Patients with diabetes had more previous hospitalization, a clinically significant disability, and more need for a urinary catheter in comparison with subjects without diabetes. Patients affected by diabetes took more drugs, both at admission, at in-hospital stay, at discharge, and at 1-year follow-up. Thirty-five comorbidities were more frequent in patients with diabetes, and the first five were hypertension (57.1%), ischemic heart disease (31.4%), chronic renal failure (28.8%), atrial fibrillation (25.6%), and chronic obstructive pulmonary disease (22.7%). Heart rate was an independent predictor of in-hospital mortality. At 1-year follow-up, cancer and male sex were strongly independently associated with mortality. Conclusions: Our findings showed the severity of the impact of diabetes and its comorbidities in the real life of internal medicine and geriatric wards, and provide data to be used for a better tailored management of elderly in-patients with diabetes. |
| Document Type: |
article in journal/newspaper |
| File Description: |
STAMPA |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/35052252; info:eu-repo/semantics/altIdentifier/wos/WOS:000756915700001; volume:10; issue:1; firstpage:86; journal:HEALTHCARE; https://hdl.handle.net/11391/1503782 |
| DOI: |
10.3390/healthcare10010086 |
| Availability: |
https://hdl.handle.net/11391/1503782; https://doi.org/10.3390/healthcare10010086 |
| Accession Number: |
edsbas.B25A816D |
| Database: |
BASE |